Evidence map›Paper›PMID 31421976›Full record

ReviewThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2019

Structured review of post-cardiotomy extracorporeal membrane oxygenation: Part 2-pediatric patients.

Roberto Lorusso, Giuseppe Maria Raffa, Mariusz Kowalewski, Khalid Alenizy, Niels Sluijpers, Maged Makhoul, Daniel Brodie, Mike McMullan, I-Wen Wang, Paolo Meani and 16 more

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Early Outcomes of Extracorporeal Membrane Oxygenation in Congenital Heart Surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026
    Article
  3. Extracorporeal membrane oxygenation (ECMO) in pediatric congenital heart disease: a comprehensive review.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 20 institutions in 8 countries.

Roberto LorussoCardio-Thoracic Surgery Department, Heart & Vascular Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
Giuseppe Maria RaffaDepartment for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS-ISMETT (Istituto Mediterraneo per I Trapianti e Terapie ad alta specializzazione), Palermo, Italy. Electronic address: giuseppe.raffa78@gmail.com.
Mariusz KowalewskiDepartment of Cardiac Surgery, Antoni Jurasz Memorial University Hospital, Bydgoszcz, Poland.
Khalid AlenizyCardio-Thoracic Surgery Department, Heart & Vascular Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
Niels SluijpersCardio-Thoracic Surgery Department, Heart & Vascular Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
Maged MakhoulCardio-Thoracic Surgery Department, Heart & Vascular Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
Daniel BrodieDivision of Pulmonary & Critical Care Medicine, Columbia University, New York, New York.
Mike McMullanCardiac Surgery Unit, Seattle Children Hospital, Seattle, Washington.
I-Wen WangCardiac Transplantation and Mechanical Circulatory Support Unit, Indiana University School of Medicine, Health Methodist Hospital, Indianapolis, Indiana.
Paolo MeaniHeart & Vascular Centre, Cardiology Department, Maastricht University Medical Centre, Maastricht, The Netherlands.
Graeme MacLarenCardiothoracic Intensive Care Unit, National University of Singapore, Singapore.
Heidi DaltonINOVA Fairfax Medical Centre, Adult and Pediatric ECMO Service, Falls Church, Virginia.
Ryan BarbaroDivision of Pediatric Critical Care and Child Health Evaluation and Research Unit, Ann Arbor, Michigan.
Xaotong HouCentre for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Nicholas CavarocchiSurgical Cardiac Care Unit, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
Yih-Sharng ChenCardiovascular Surgery & Ped Cardiovascular Surgery, National Taiwan University Hospital, Taipei, China.
Ravi ThiagarajanCardiac Intensive Care Unit, Boston Children's Hospital, Boston, Massachusetts.
Peta AlexanderCardiac Intensive Care Unit, Boston Children's Hospital, Boston, Massachusetts.
Bahaaldin AlsoufiDepartment of Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine, Norton Children's Hospital, Louisville, Kentucky.
Christian A BermudezDepartment of Cardiothoracic Surgery, Philadelphia, Pennsylvania.
Ashish S ShahDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Jonathan HaftSection of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Lilia OretoMediterranean Pediatric Cardiology Center, Bambino Gesù Pediatric Hospital, Taormina, Messina, Italy.
David A D'AlessandroCardio-Thoracic Surgery Department, Massachusetts Medical Center, Boston, Massachusetts.
Udo BoekenCardiovascular Surgery Unit, University of Düsseldorf, Düsseldorf, Germany.
Glenn WhitmanCardiovascular Surgery Intensive Care Unit and Heart Transplant, Johns Hopkins Hospital, Baltimore, Maryland.
Maastricht University Medical Centre · NLBoston Children's Hospital · USAntoni Jurasz University Hospital · PLBambino Gesù Children's Hospital · ITBeijing Anzhen Hospital · CNBoston Medical Center · USColumbia University · USHeinrich Heine University Düsseldorf · DEIndiana University School of MedicineInova Fairfax Hospital · USIstituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione · ITJohns Hopkins Hospital · USNational Taiwan University Hospital · TWNational University of Singapore · SGPhiladelphia University · USSeattle Children's Hospital · USThomas Jefferson University Hospital · USUniversity of Louisville · USUniversity of Michigan–Ann Arbor · USVanderbilt University Medical Center · US

Funding

Training to Advance Care Through Implementation Science in Cardiac And Lung Illnesses (TACTICAL)K12HL138039 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BARNES, GEOFFREY DOUGLAS, PRESCOTT, HALLIE CHRISTINE · 2017 to 2021
$3.1M
NHLBI NIH HHS K12 HL138039
6 · The paper itself

Abstract

Veno-arterial extracorporeal membrane oxygenation (ECMO) is established therapy for short-term circulatory support for children with life-treating cardiorespiratory dysfunction. In children with congenital heart disease (CHD), ECMO is commonly used to support patients with post-cardiotomy shock or complications including intractable arrhythmias, cardiac arrest, and acute respiratory failure. Cannulation configurations include central, when the right atrium and aorta are utilized in patients with recent sternotomy, or peripheral, when cannulation of the neck or femoral vessels are used in non-operative patients. ECMO can be used to support any form of cardiac disease, including univentricular palliated circulation. Although veno-arterial ECMO is commonly used to support children with CHD, veno-venous ECMO has been used in selected patients with hypoxemia or ventilatory failure in the presence of good cardiac function. ECMO use and outcomes in the CHD population are mainly informed by single-center studies and reports from collated registry data. Significant knowledge gaps remain, including optimal patient selection, timing of ECMO deployment, duration of support, anti-coagulation, complications, and the impact of these factors on short- and long-term outcomes. This report, therefore, aims to present a comprehensive overview of the available literature informing patient selection, ECMO management, and in-hospital and early post-discharge outcomes in pediatric patients treated with ECMO for post-cardiotomy cardiorespiratory failure.

Indexed as

Cardiac Surgical ProceduresExtracorporeal Membrane OxygenationChildHeart Defects, CongenitalHumansPostoperative ComplicationsTreatment Outcomecardiac surgical procedureschildcongenitalextracorporeal membrane oxygenationpost-cardiotomy cardiogenic shockpost-cardiotomy circulatory assistance

Identifiers

PMID31421976
PMCPMC7987375
OpenAlexW2982045285

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.