Evidence map›Paper›PMID 31421642›Full record

ReviewThrombosis and haemostasis2019

Thrombogenicity and Antithrombotic Strategies in Structural Heart Interventions and Nonaortic Cardiac Device Therapy-Current Evidence and Practice.

Tobias Geisler, Rezo Jorbenadze, Aron-Frederik Popov, Karin L Mueller, Dominik Rath, Michal Droppa, Juergen Schreieck, Peter Seizer, Robert F Storey, Steen D Kristensen and 7 more

Erratum issuedOpen access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Thrombosis and haemostasis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Impact of pulmonary hypertension on outcomes after TEER in patients suffering from mitral regurgitation.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  3. Article
  4. Article
  5. Transcatheter Mitral Valve Replacement and Thrombosis: A Review.Frontiers in cardiovascular medicine · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 7 countries.

Tobias GeislerDepartment of Cardiology and Angiology, University Hospital, Eberhard-Karls University of Tübingen, Tübingen, Germany.
Rezo JorbenadzeDepartment of Cardiology and Angiology, University Hospital, Eberhard-Karls University of Tübingen, Tübingen, Germany.
Aron-Frederik PopovDepartment of Thoracic and Cardiovascular Surgery, University Medical Center Tübingen, Eberhard-Karls University of Tübingen, Tübingen, Germany.
Karin L MuellerDepartment of Cardiology and Angiology, University Hospital, Eberhard-Karls University of Tübingen, Tübingen, Germany.
Dominik RathDepartment of Cardiology and Angiology, University Hospital, Eberhard-Karls University of Tübingen, Tübingen, Germany.
Michal DroppaDepartment of Cardiology and Angiology, University Hospital, Eberhard-Karls University of Tübingen, Tübingen, Germany.ORCID 0000-0001-5807-7615
Juergen SchreieckDepartment of Cardiology and Angiology, University Hospital, Eberhard-Karls University of Tübingen, Tübingen, Germany.
Peter SeizerDepartment of Cardiology and Angiology, University Hospital, Eberhard-Karls University of Tübingen, Tübingen, Germany.
Robert F StoreyDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.
Steen D KristensenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Andrea RubboliDivision of Cardiology, Department of Cardiovascular Disease-AUSL Romagna, Ospedale S. Maria delle Croci, Ravenna, Italy.
Diana GorogNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Daniel AradiHeart Center Balatonfured, Balatonfured, Hungary.
Dirk SibbingDepartment of Cardiology, LMU München, Munich, Germany.
Kurt Huber3rd Department of Medicine, Cardiology and Intensive Care Medicine, Wilhelminenhospital, Vienna, Austria.
Meinrad GawazDepartment of Cardiology and Angiology, University Hospital, Eberhard-Karls University of Tübingen, Tübingen, Germany.
Jur Ten BergDepartment of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
University of Tübingen · DEAarhus University Hospital · DKLMU Klinikum · DEOspedale "Santa Maria delle Croci" di Ravenna · ITSemmelweis University · HUSigmund Freud Privatuniversität Wien · ATSt. Antonius Ziekenhuis · NLUniversity of Hertfordshire · GBUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the number of, and the indications for, structural heart interventions are increasing worldwide, the optimal secondary prevention to reduce device thrombosis is becoming more important. To date, most of the recommendations are empiric. The current review discusses mechanisms behind device-related thrombosis, the available evidence with regard to antithrombotic regimen after cardiac device implantation, as well as providing an algorithm for identification of risk factors for device thrombogenicity and for management of device thrombosis after implantation of patent foramen ovale and left atrial appendage occluders, MitraClips/transcatheter mitral valve replacement, pacemaker leads, and left ventricular assist devices. Of note, the topic of antithrombotic therapy and thrombogenicity of prostheses in aortic position (transcatheter aortic valve replacement, surgical, mechanical, and bioprostheses) is not part of the present article and is discussed in detail in other contemporary focused articles.

Indexed as

AlgorithmsBioprosthesisCardiac CatheterizationCardiac Surgical ProceduresCardiologyFibrinolytic AgentsForamen Ovale, PatentHeart-Assist DevicesHeart FailureHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansMitral ValveProsthesis DesignRisk AssessmentRisk FactorsFibrinolytic Agents

Identifiers

PMID31421642
OpenAlexW2968138215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.