ArticleiScience2019
A Neuromorphic Prosthesis to Restore Communication in Neuronal Networks.
Article in iScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed, 73 citations in OpenAlex.
- Microfluidic platforms for probing spontaneous functional recovery in hierarchically modular neuronal networks.Communications engineering · 2026Article
- Advancing neuroengineering with Neuromorphic Twins.Nature communications · 2026Review
- Spiking neural networks provide accurate and time-efficient models for whisker stimulus classification of the awake mouse.Frontiers in neuroscience · 2026Article
- Neural vs Neuromorphic Interfaces: Where Are We Standing?Chemical reviews · 2025Review
- Manipulation of neuronal activity by an artificial spiking neural network implemented on a closed-loop brain-computer interface in non-human primates.Journal of neural engineering · 2025Article
- Opportunities and Challenges of Brain-on-a-Chip Interfaces.Cyborg and bionic systems (Washington, D.C.) · 2025Review
- Lattice physics approaches for neural networks.iScience · 2024Review
- Neuromorphic neuromodulation: Towards the next generation of closed-loop neurostimulation.PNAS nexus · 2024Review
- Neuromorphic hardware for somatosensory neuroprostheses.Nature communications · 2024Review
- Real-time multicompartment Hodgkin-Huxley neuron emulation on SoC FPGA.Frontiers in neuroscience · 2024Article
- Microfluidic Bi-Layer Platform to Study Functional Interaction between Co-Cultured Neural Networks with Unidirectional Synaptic Connectivity.Micromachines · 2023Article
- Nanomaterial-based microelectrode arrays for in vitro bidirectional brain-computer interfaces: a review.Microsystems & nanoengineering · 2023Review
- ReplaceNet: real-time replacement of a biological neural circuit with a hardware-assisted spiking neural network.Frontiers in neuroscience · 2023Article
- Neuromorphic-Based Neuroprostheses for Brain Rewiring: State-of-the-Art and Perspectives in Neuroengineering.Brain sciences · 2022Review
- Advances in construction and modeling of functional neural circuits in vitro.Neurochemical research · 2022Article
- An improved platform for cultured neuronal network electrophysiology: multichannel optogenetics integrated with MEAs.European biophysics journal : EBJ · 2022Article
- Will microfluidics enable functionally integrated biohybrid robots?Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Classification of Whisker Deflections From Evoked Responses in the Somatosensory Barrel Cortex With Spiking Neural Networks.Frontiers in neuroscience · 2022Article
- Mimicking efferent nerves using a graphdiyne-based artificial synapse with multiple ion diffusion dynamics.Nature communications · 2021Article
- Electrophysiology Read-Out Tools for Brain-on-Chip Biotechnology.Micromachines · 2021Review
Corrections and comments
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Authors and funding
17 authors at 6 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent advances in bioelectronics and neural engineering allowed the development of brain machine interfaces and neuroprostheses, capable of facilitating or recovering functionality in people with neurological disability. To realize energy-efficient and real-time capable devices, neuromorphic computing systems are envisaged as the core of next-generation systems for brain repair. We demonstrate here a real-time hardware neuromorphic prosthesis to restore bidirectional interactions between two neuronal populations, even when one is damaged or missing. We used in vitro modular cell cultures to mimic the mutual interaction between neuronal assemblies and created a focal lesion to functionally disconnect the two populations. Then, we employed our neuromorphic prosthesis for bidirectional bridging to artificially reconnect two disconnected neuronal modules and for hybrid bidirectional bridging to replace the activity of one module with a real-time hardware neuromorphic Spiking Neural Network. Our neuroprosthetic system opens avenues for the exploitation of neuromorphic-based devices in bioelectrical therapeutics for health care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.