Evidence map›Paper›PMID 31421234›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2020

The Centrality of Doubting and Checking in the Network Structure of Obsessive-Compulsive Symptom Dimensions in Youth.

Matti Cervin, Sean Perrin, Elin Olsson, Kristina Aspvall, Daniel A Geller, Sabine Wilhelm, Joseph McGuire, Luisa Lázaro, Agustin E Martínez-González, Barbara Barcaccia and 12 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 15 institutions in 5 countries.

Matti CervinLund University, Lund, Sweden; Skåne Child and Adolescent Psychiatry, Lund, Sweden. Electronic address: matti.cervin@med.lu.se.
Sean PerrinLund University, Lund, Sweden.
Elin OlssonSkåne Child and Adolescent Psychiatry, Lund, Sweden.
Kristina AspvallKarolinska Institutet and Stockholm Health Care Services, Stockholm, Sweden.
Daniel A GellerMassachusetts General Hospital and Harvard Medical School, Boston Massachusetts.
Sabine WilhelmMassachusetts General Hospital and Harvard Medical School, Boston Massachusetts.
Joseph McGuireJohns Hopkins University School of Medicine, Baltimore Maryland.
Luisa LázaroHospital Clínic, IDIBAPS, CIBERSAM, University of Barcelona, Spain.
Agustin E Martínez-GonzálezUniversity of Alicante, Alicante, Spain.
Barbara BarcacciaSapienza University of Rome, Italy.
Andrea PozzaUniversity of Florence, Italy.
Wayne K GoodmanBaylor College of Medicine, Houston, Texas.
Tanya K MurphyUniversity of South Florida, Tampa.
İsmail SeçerAtatürk University, Erzurum, Turkey.
José A PiquerasUniversity Miguel Hernandez de Elche, Alicante, Spain.
Tiscar Rodríguez-JiménezThe Catholic University of San Antonio, Murcia, Spain.
Antonio GodoyUniversity of Malaga, Malaga, Spain.
Ana I Rosa-AlcázarUniversity of Murcia, Murcia, Spain.
Ángel Rosa-AlcázarCatholic University of Murcia, Murcia, Spain.
Beatriz M Ruiz-GarcíaUniversity of Murcia, Murcia, Spain.
Eric A StorchBaylor College of Medicine, Houston, Texas.
David Mataix-ColsKarolinska Institutet and Stockholm Health Care Services, Stockholm, Sweden.
Universidad Católica de Murcia · ESBaylor College of Medicine · USHarvard University · USKarolinska Institutet · SELund University · SEAtatürk University · TRCentro de Investigación Biomédica en Red de Salud Mental · ESJohns Hopkins University · USSapienza University of Rome · ITUniversidad de Málaga · ESUniversidad de Murcia · ESUniversitat de Miguel Hernández d'Elx · ESUniversity of Alicante · ESUniversity of Florence · ITUniversity of South Florida · US

Funding

2/2-D-Cycloserine Augmentation of CBT for Pediatric OCDR01MH093402 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI GELLER, DANIEL A · 2011 to 2014
$1.7M
1/2-D-Cycloserine Augmentation of CBT for Pediatric OCDR01MH093381 · NIMH · UNIVERSITY OF SOUTH FLORIDA · PI STORCH, ERIC A. · 2011 to 2014
$1.2M
NIMH NIH HHS R01 MH093381NIMH NIH HHS R01 MH093402
6 · The paper itself

Abstract

objectiveObsessive-compulsive disorder (OCD) is a heterogeneous condition with well-established symptom dimensions across the lifespan. The objective of the present study was to use network analysis to investigate the internal structure of these dimensions in unselected schoolchildren and in children with OCD.

methodWe estimated the network structure of OCD symptom dimensions in 6,991 schoolchildren and 704 children diagnosed with OCD from 18 sites across 6 countries. All participants completed the Obsessive-Compulsive Inventory-Child Version.

resultsIn both the school-based and clinic-based samples, the OCD dimensions formed an interconnected network with doubting/checking emerging as a highly central node, that is, having strong connections to other symptom dimensions in the network. The centrality of the doubting/checking dimension was consistent across countries, sexes, age groups, clinical status, and tic disorder comorbidity. Network differences were observed for age and sex in the school-based but not the clinic-based samples.

conclusionThe centrality of doubting/checking in the network structure of childhood OCD adds to classic and recent conceptualizations of the disorder in which the important role of doubt in disorder severity and maintenance is highlighted. The present results suggest that doubting/checking is a potentially important target for further research into the etiology and treatment of childhood OCD.

Indexed as

Obsessive-Compulsive DisorderTic DisordersAdolescentChildComorbidityEmotionsHumansSeverity of Illness Indexdimensionsnetwork analysisobsessive-compulsive disorderObsessive-Compulsive Inventory

Identifiers

PMID31421234
PMCPMC7219532
OpenAlexW2966875637

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.