ArticleClinical genetics2020
Urogenital and pelvic complications in the Ehlers-Danlos syndromes and associated hypermobility spectrum disorders: A scoping review.
Article in Clinical genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Extracutaneous features and complications of the Ehlers-Danlos syndromes: A systematic review.Frontiers in medicine · 2023Pooled it
- Cases - Ehlers-Danlos syndromes: Review on the urologic implications.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Article
- Beyond antifungals: vaginal ceramides as a barrier-restorative strategy for recurrent vulvovaginal candidiasis in Ehlers-Danlos syndrome.Annals of medicine and surgery (2012) · 2026Article
- Females with hypermobile Ehlers-Danlos syndrome self-report more sexual problems than chronic pain controls without hypermobility, males, or patients with hypermobile spectrum disorders.Frontiers in reproductive health · 2026Article
- Bilateral orchidopexy for intermittent testicular torsion.BJUI compass · 2024Article
- The Spider: a visual, multisystemic symptom impact questionnaire for people with hypermobility-related disorders-validation in adults.Clinical rheumatology · 2024Observational
- Chronic Pain and Joint Hypermobility: A Brief Diagnostic Review for Clinicians and the Potential Application of Infrared Thermography in Screening Hypermobile Inflamed Joints.The Yale journal of biology and medicine · 2024Review
- Exploring the biopsychosocial impact of hypermobility spectrum disorders and Ehlers-Danlos syndrome in an adult population: a protocol for a scoping review.Systematic reviews · 2024Article
- Concomitant uterus agenesia and Marfan syndrome with systemic sclerosis: A rare case report.Clinical case reports · 2024Article
- Comorbidities and neurosurgical interventions in a cohort with connective tissue disorders.Frontiers in neurology · 2024Article
- Co-Created Solutions for Perinatal Professionals and Childbearing Needs for People with Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders.International journal of environmental research and public health · 2023Article
- Anorectal manometry for the diagnosis of pelvic floor disorders in patients with hypermobility spectrum disorders and hypermobile Ehlers-Danlos syndrome.BMC gastroenterology · 2022Article
- Exercise and Rehabilitation in People With Ehlers-Danlos Syndrome: A Systematic Review.Archives of rehabilitation research and clinical translation · 2022Review
- High rate of dyspareunia and probable vulvodynia in Ehlers-Danlos syndromes and hypermobility spectrum disorders: An online survey.American journal of medical genetics. Part C, Seminars in medical genetics · 2021Article
- Pain Symptomatology and Management in Pediatric Ehlers-Danlos Syndrome: A Review.Children (Basel, Switzerland) · 2020Review
- Pregnancy management in a patient with stickler syndrome.Molecular genetics & genomic medicine · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The Ehlers-Danlos syndromes (EDS) and associated hypermobility spectrum disorders (HSD) are a heterogenous group of connective tissue disorders associated with significant morbidity. The urogenital aspects of these disorders are understudied and there is little guidance on the prevalence, types, or outcomes of urogenital complications in EDS/HSD. Our objective was to perform a scoping review to characterize and synthesize the literature reporting urogenital and pelvic complications in EDS/HSD patients. We performed a systematic search of three databases (Medline, CINAHL, Embase) to January 2019. English language, full-text articles reporting on urogenital or pelvic complications in EDS/HSD were included. A total of 105 studies were included (62 case reports/series, 43 observational) involving patients with hypermobile (23%), vascular (20%), classical (12%) EDS, and HSD (24%). Some studies looked at multiple subtypes (11%) or did not report subtype (33%). Reported complications included urinary (41%), gynecological (36%), obstetrical (25%), renal (9%), and men's health problems (7%), with some studies reporting on multiple areas. Urinary and gynecological complications were most prevalent in patients with HSD, while a broad range of complications were reported in EDS. While further research is required, results suggest a higher index of suspicion for urogenital problems is probably warranted in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.