ArticleCanadian journal of public health = Revue canadienne de sante publique2019
Cost-benefit analysis of a population-based education program on the wise use of antibiotics.
Article in Canadian journal of public health = Revue canadienne de sante publique, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Economic evaluation of antimicrobial stewardship in primary care: a systematic review and quality assessment.The Journal of antimicrobial chemotherapy · 2022Pooled it
- A pragmatic randomized trial of a primary care antimicrobial stewardship intervention in Ontario, Canada.BMC family practice · 2021Trial
- Mailed Audit and Feedback for Antibiotic Prescribing in Primary Care.JAMA network open · 2026Article
- Health system barriers to the implementation of the national action plan to combat antimicrobial resistance in Vietnam: a scoping review.Antimicrobial resistance and infection control · 2024Article
- Impact analysis of infant antibiotic exposure on the burden of asthma: a simulation modeling study.Frontiers in allergy · 2024Article
- Article
- Development and evaluation of a primary care antimicrobial stewardship program (PC-ASP) in Toronto, Ontario, Canada.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn 2005, the Do Bugs Need Drugs (DBND) program was imported to British Columbia (BC) from Alberta with the goal of reducing unnecessary antibiotic use in the community. The objective of this study was to estimate the impact of the program on antibiotic-associated costs and cost-benefit.
methodsWe used data on antibiotic prescription and costs from BC PharmaNet for the period of 1996 to 2014. We conducted interrupted time series regression to formally interpret the impact of the DBND program.
resultsThe average monthly prescription rate fell by 14.5%, from 54.3 to 46.4 per 1000 population between 2005 and 2014. The proportionate contribution of macrolide prescription decreased from 19.2% in 2005 to 13.2% in 2014 and for quinolones decreased from 13.1% in 2005 to 12% in 2014. The proportion of prescriptions for both penicillins and tetracyclines increased by > 35.5%. Before the program, the average monthly cost of antibiotics was increasing by CAD $8.12 per 1000 population (p < 0.001). After program introduction, average monthly cost decreased by CAD $18.19 per 1000 population (p < 0.001), creating an annual savings for BC in 2014 of CAD $83.6 million. In 2014, one Canadian dollar spent on the DBND program was associated with conservative savings of CAD $76.20.
conclusionSignificant cost savings have been observed in association with a community antimicrobial stewardship program focused on both public and prescribers. Such programs are an effective strategy in cost-benefit terms and should therefore be considered for universal adoption in Canadian healthcare systems.
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