ArticleParasitology research2019
Infection patterns, clinical significance, and genetic characteristics of Enterocytozoon bieneusi and Giardia duodenalis in dairy cattle in Jiangsu, China.
Article in Parasitology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Global prevalence of Giardia infection in nonhuman mammalian hosts: A systematic review and meta-analysis of five million animals.PLoS neglected tropical diseases · 2025Pooled it
- Genotyping and Age-Related Distribution of Enterocytozoon bieneusi in Preweaned Calves in Türkiye.Acta parasitologica · 2025Article
- Molecular Epidemiology ofMicroorganisms · 2025Article
- Investigation of Infection ofVeterinary sciences · 2025Article
- Molecular prevalence and genetic characterization of Enterocytozoon bieneusi in cattle in a dairy farm in Türkiye.BMC veterinary research · 2025Article
- Prevalence and genotyping of Enterocytozoon bieneusi in cattle from Shanxi and Inner Mongolia, China.Scientific reports · 2025Article
- Prevalence and molecular characterization of Cryptosporidium spp., Enterocytozoon bieneusi, and Giardia duodenalis in dairy cattle in Ningxia, northwestern China.Veterinary research communications · 2024Article
- Prevalence and Molecular Characterization ofAnimals : an open access journal from MDPI · 2024Article
- First report of Giardia duodenalis in dairy cattle and beef cattle in Shanxi, China.Molecular biology reports · 2024Article
- Molecular detection and genetic characteristics of Giardia duodenalis in dairy cattle from large-scale breeding farms in Xinjiang, China.Parasitology research · 2024Article
- Molecular prevalence and genotype identification ofFrontiers in veterinary science · 2024Article
- Prevalence and molecular characterization of Giardia duodenalis in dairy cattle in Central Inner Mongolia, Northern China.Scientific reports · 2023Article
- Molecular detection and characterization ofFrontiers in veterinary science · 2023Article
- Molecular Detection and Genotyping ofAnimals : an open access journal from MDPI · 2022Article
- Prevalence and molecular characterization of Cryptosporidium spp. and Enterocytozoon bieneusi from large-scale cattle farms in Anhui Province, China.The Journal of veterinary medical science · 2022Article
- Prevalence and multilocus genotyping ofFrontiers in veterinary science · 2022Article
- Zoonotic giardiasis: an update.Parasitology research · 2021Review
- Prevalence and Novel Genotypes Identification ofAnimals : an open access journal from MDPI · 2021Article
- Molecular Detection and Characterization ofVeterinary sciences · 2021Article
- Population genetic analysis suggests genetic recombination is responsible for increased zoonotic potential ofOne health (Amsterdam, Netherlands) · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The infection patterns and clinical significance of Enterocytozoon bieneusi and Giardia duodenalis in dairy cattle remain poorly investigated despite their common occurrence. Data on the genetic diversity are also needed to understand the transmission and human-infective potential of the two pathogens. In this study, fecal specimens from 1366 dairy cattle on a large farm were examined for the presence and genotype distribution of E. bieneusi and G. duodenalis by PCR and DNA sequencing. The overall infection rates of E. bieneusi and G. duodenalis were 13.0% and 20.6%, respectively. Pre-weaned calves had significantly higher infection rates of both pathogens than post-weaned and adult cattle (P < 0.001), with peak occurrence of the pathogens in animals of 7-12 weeks. In both pre- and post-weaned calves, animals with diarrhea were 2.1-3.0 times more likely to be infected with either pathogen than those without diarrhea (P < 0.01). The E. bieneusi identified belonged to five genotypes, including J (n = 138), I (n = 21), BEB4 (n = 10), Type IV (n = 1), and a novel genotype CHC17 (n = 1). Genotype J was the dominant one in all age groups, whereas genotype I was only identified in calves of 6-11 weeks. Genotyping of G. duodenalis at three genetic loci identified assemblage E (n = 278), assemblage A (n = 2), and concurrence of the two (n = 1). Altogether, 13, 7 and 10 subtypes of assemblage E were detected at the bg, gdh, and tpi loci, respectively, forming 65 multilocus genotypes. The formation of two major clusters of MLGs in eBURST analysis indicated that intra-assemblage genetic recombination of two dominant MLGs could have led to the high genetic heterogeneity within assemblage E on a single farm. Results of this study provide much needed data on the pathogenicity of E. bieneusi and G. duodenalis in pre- and post-weaned calves. The clinical significance of the two pathogens in dairy cattle warrants further investigations.
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