Evidence map›Paper›PMID 31420565›Full record

ArticleScientific reports2019

Insights into Pasteurellaceae carriage dynamics in the nasal passages of healthy beef calves.

A C Thomas, M Bailey, M R F Lee, A Mead, B Morales-Aza, R Reynolds, B Vipond, A Finn, M C Eisler

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  7. Microorganisms · 2022
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  8. Review
  9. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

A C ThomasBristol Veterinary School, University of Bristol, Langford, UK. amyc.thomas@bristol.ac.uk.ORCID http://orcid.org/0000-0002-2658-4126
M BaileyBristol Veterinary School, University of Bristol, Langford, UK.
M R F LeeBristol Veterinary School, University of Bristol, Langford, UK.
A MeadRothamsted Research, Harpenden, UK.
B Morales-AzaBristol Children's Vaccine Centre, University of Bristol, Bristol, UK.
R ReynoldsSchool of Population Health Sciences, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0003-4643-9556
B VipondPublic Health Laboratory Bristol, Public Health England, Bristol, UK.
A FinnBristol Children's Vaccine Centre, University of Bristol, Bristol, UK.
M C EislerBristol Veterinary School, University of Bristol, Langford, UK. mark.eisler@bristol.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BBS/E/C/000I0320Biotechnology and Biological Sciences Research Council BBS/E/C/000J0100
6 · The paper itself

Abstract

We investigated three bovine respiratory pathobionts in healthy cattle using qPCR optimised and validated to quantify Histophilus somni, Mannheimia haemolytica and Pasteurella multocida over a wide dynamic range. A longitudinal study was conducted to investigate the carriage and density of these bacteria in the nasal passages of healthy beef calves (N = 60) housed over winter in an experimental farm setting. The three pathobiont species exhibited remarkably different carriage rates and density profiles. At housing, high carriage rates were observed for P. multocida (95%), and H. somni (75%), while fewer calves were positive for M. haemolytica (13%). Carriage rates for all three bacterial species declined over the 75-day study, but not all individuals became colonised despite sharing of environment and airspace. Colonisation patterns ranged from continuous to intermittent and were different among pathobiont species. Interval-censored exponential survival models estimated the median duration of H. somni and P. multocida carriage at 14.8 (CI

Indexed as

AnimalsBacterial LoadCarrier StateCattleCattle DiseasesDNA, BacterialLongitudinal StudiesMaleMannheimia haemolyticaNasal CavityPasteurellaceaePasteurellaceae InfectionsPasteurella multocidaPolymerase Chain ReactionDNA, Bacterial

Identifiers

PMID31420565
PMCPMC6697682

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.