Evidence map›Paper›PMID 31420546›Full record

ArticleNature communications2019

Memory-guided microsaccades.

Konstantin F Willeke, Xiaoguang Tian, Antimo Buonocore, Joachim Bellet, Araceli Ramirez-Cardenas, Ziad M Hafed

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 90 citations in OpenAlex.

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  9. Stimulus representations in visual cortex shaped by spatial attention and microsaccades.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  19. Linking Cognitive Integrity to Working Memory Dynamics in the Aging Human Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Konstantin F WillekeWerner Reichardt Centre for Integrative Neuroscience, Tuebingen University, 72076, Tuebingen, Germany.ORCID http://orcid.org/0000-0003-4445-6408
Xiaoguang TianWerner Reichardt Centre for Integrative Neuroscience, Tuebingen University, 72076, Tuebingen, Germany.
Antimo BuonocoreWerner Reichardt Centre for Integrative Neuroscience, Tuebingen University, 72076, Tuebingen, Germany.ORCID http://orcid.org/0000-0003-3917-510X
Joachim BelletWerner Reichardt Centre for Integrative Neuroscience, Tuebingen University, 72076, Tuebingen, Germany.
Araceli Ramirez-CardenasWerner Reichardt Centre for Integrative Neuroscience, Tuebingen University, 72076, Tuebingen, Germany.ORCID http://orcid.org/0000-0003-2034-4188
Ziad M HafedWerner Reichardt Centre for Integrative Neuroscience, Tuebingen University, 72076, Tuebingen, Germany. ziad.m.hafed@cin.uni-tuebingen.de.ORCID http://orcid.org/0000-0001-9968-119X
Max Planck Institute for Developmental Biology · DEHertie Institute for Clinical Brain Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite strong evidence to the contrary in the literature, microsaccades are overwhelmingly described as involuntary eye movements. Here we show in both human subjects and monkeys that individual microsaccades of any direction can easily be triggered: (1) on demand, based on an arbitrary instruction, (2) without any special training, (3) without visual guidance by a stimulus, and (4) in a spatially and temporally accurate manner. Subjects voluntarily generated instructed "memory-guided" microsaccades readily, and similarly to how they made normal visually-guided ones. In two monkeys, we also observed midbrain superior colliculus neurons that exhibit movement-related activity bursts exclusively for memory-guided microsaccades, but not for similarly-sized visually-guided movements. Our results demonstrate behavioral and neural evidence for voluntary control over individual microsaccades, supporting recently discovered functional contributions of individual microsaccade generation to visual performance alterations and covert visual selection, as well as observations that microsaccades optimize eye position during high acuity visually-guided behavior.

Indexed as

AdultAnimalsFemaleHumansMacaca mulattaMaleMemoryMemory, Short-TermNeural PathwaysNeuronsSaccadesSpatial MemorySuperior ColliculiYoung Adult

Identifiers

PMID31420546
PMCPMC6697692
OpenAlexW2967068560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.