Evidence map›Paper›PMID 31420527›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2019

Differential Roles of Accumbal GSK3

Xiangdang Shi, Jeffrey L Barr, Eva von Weltin, Cassandra Wolsh, Ellen M Unterwald

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Decrease of glycogen synthase kinase 3β phosphorylation in the rat nucleus accumbens shell is necessary for amphetamineinduced conditioned locomotor activity.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2022
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiangdang ShiCenter for Substance Abuse Research and Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania xiangdang.shi@temple.edu.
Jeffrey L BarrCenter for Substance Abuse Research and Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Eva von WeltinCenter for Substance Abuse Research and Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Cassandra WolshCenter for Substance Abuse Research and Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Ellen M UnterwaldCenter for Substance Abuse Research and Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Temple University · US

Funding

Pilot Projects Core (PPC)P30DA013429 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI Munir Gunes Kutlu · 2000 to 2026
$34.6M
GSK3beta signaling in cocaine reward and memoryR01DA043988 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI UNTERWALD, ELLEN M · 2017 to 2021
$2.1M
NIDA NIH HHS P30 DA013429NIDA NIH HHS R01 DA043988
6 · The paper itself

Abstract

Previous research has demonstrated that activity of glycogen synthase kinase-3 (GSK3) is necessary for the rewarding effects of cocaine. In the present study, a conditional GSK3

Indexed as

3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-IsomerAnalgesics, Non-NarcoticAnimalsAvoidance LearningCocaineConditioning, PsychologicalGlycogen Synthase Kinase 3 betaMemoryMiceMice, TransgenicMorphineNucleus AccumbensRandom Allocation3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-IsomerAnalgesics, Non-NarcoticCocaineGlycogen Synthase Kinase 3 betaMorphine

Identifiers

PMID31420527
PMCPMC6800444
OpenAlexW2967083925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.