Evidence map›Paper›PMID 31420510›Full record

ReviewProceedings of the National Academy of Sciences of the United States of America2019

Intermembrane transport: Glycerophospholipid homeostasis of the Gram-negative cell envelope.

Matthew J Powers, M Stephen Trent

Open access · bronzeAbstract readReview
In one paragraph

Review in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 68 citations in OpenAlex.

  1. A surface-exposed cardiolipin synthase provides an unexpected paradigm for maintaining the Gram-negative outer membrane.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Review
  4. Following phospholipid transfer through the OmpFProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Lipid Trafficking in Diverse Bacteria.Accounts of chemical research · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. The Mla system and its role in maintaining outer membrane barrier function inFrontiers in cellular and infection microbiology · 2024
    Article
  14. Article
  15. International journal of molecular sciences · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew J PowersDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602.
M Stephen TrentDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602; strent@uga.edu.ORCID 0000-0001-6134-1800
University of Georgia · US

Funding

Development of a novel vaccine platform: Surface Antigen/Adjuvant Vaccine Engineering (SAAVE)R01AI129940 · NIAID · UNIVERSITY OF GEORGIA · PI TRENT, MICHAEL STEPHEN · 2017 to 2021
$3.3M
The Outer Surface of Vibrio CholeraeR01AI076322 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI TRENT, MICHAEL STEPHEN · 2008 to 2017
$3.2M
Molecular mechanisms required for the maintenance of the gram-negative outer membraneR01AI138576 · NIAID · UNIVERSITY OF GEORGIA · PI TRENT, MICHAEL STEPHEN · 2018 to 2022
$2.0M
The Outer Surface of Vibrio choleraeR56AI076322 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI TRENT, MICHAEL STEPHEN · 2013 to 2013
$384k
NIAID NIH HHS R01 AI076322NIAID NIH HHS R01 AI129940NIAID NIH HHS R01 AI138576NIAID NIH HHS R56 AI076322
6 · The paper itself

Abstract

This perspective addresses recent advances in lipid transport across the Gram-negative inner and outer membranes. While we include a summary of previously existing literature regarding this topic, we focus on the maintenance of lipid asymmetry (Mla) pathway. Discovered in 2009 by the Silhavy group [J. C. Malinverni, T. J. Silhavy,

Indexed as

Biological Transport, ActiveCell MembraneCell WallGlycerophospholipidsGram-Negative BacteriaHomeostasisGlycerophospholipidsglycerophospholipidlipoproteinLPSMlaouter membrane

Identifiers

PMID31420510
PMCPMC6717313
OpenAlexW2968257264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.