Evidence map›Paper›PMID 31420457›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Paradoxical Excitatory Impact of SK Channels on Dendritic Excitability.

Tobias Bock, Suraj Honnuraiah, Greg J Stuart

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. The small conductance CaNeuropharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tobias BockEccles Institute of Neuroscience and Australian Research Council Centre of Excellence for Integrative Brain Function, John Curtin School of Medical Research, Australian National University, Canberra, 2601 Australia htb2110@columbia.edu greg.stuart@anu.edu.au.ORCID 0000-0002-7734-1183
Suraj HonnuraiahEccles Institute of Neuroscience and Australian Research Council Centre of Excellence for Integrative Brain Function, John Curtin School of Medical Research, Australian National University, Canberra, 2601 Australia.
Greg J StuartEccles Institute of Neuroscience and Australian Research Council Centre of Excellence for Integrative Brain Function, John Curtin School of Medical Research, Australian National University, Canberra, 2601 Australia htb2110@columbia.edu greg.stuart@anu.edu.au.
Australian National University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic excitability regulates how neurons integrate synaptic inputs and thereby influences neuronal output. As active dendritic events are associated with significant calcium influx they are likely to be modulated by calcium-dependent processes, such as calcium-activated potassium channels. Here we investigate the impact of small conductance calcium-activated potassium channels (SK channels) on dendritic excitability in male and female rat cortical pyramidal neurons

Indexed as

AnimalsApaminCalcium Channels, R-TypeCalcium SignalingDendritesElectrophysiological PhenomenaFemaleIndolesMaleOximesPatch-Clamp TechniquesPotassium Channel BlockersPyramidal CellsRatsRats, WistarSmall-Conductance Calcium-Activated Potassium Channels6,7-dichloro-1H-indole-2,3-dione 3-oximeApaminCalcium Channels, R-TypeIndolesOximesPotassium Channel BlockersSmall-Conductance Calcium-Activated Potassium Channelscalciumcortexdendriteexcitabilitypyramidal neuronSK channel

Identifiers

PMID31420457
PMCPMC6774406
OpenAlexW2969166483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.