Evidence map›Paper›PMID 31420437›Full record

ArticleBMJ case reports2019

Myopericarditis as a presentation of eosinophilic granulomatosus with polyangiitis (EGPA).

Mrinalini Dey, Jagdish Nair, Rajiv Sankaranarayanan, Prathap Kanagala

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mrinalini DeyDepartment of Musculoskeletal Biology I, Institute of Ageing and Chronic Disease, University of Liverpool Faculty of Health and Life Sciences, Liverpool, UK.ORCID http://orcid.org/0000-0001-6858-4338
Jagdish NairDepartment of Academic Rheumatology, Aintree University Hospitals NHS Foundation Trust, Liverpool, UK.
Rajiv SankaranarayananDepartment of Cardiology, Aintree University Hospitals NHS Foundation Trust, Liverpool, UK.
Prathap KanagalaDepartment of Cardiology, Aintree University Hospitals NHS Foundation Trust, Liverpool, UK.ORCID http://orcid.org/0000-0001-6739-5607

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 60-year-old woman was admitted to the hospital with worsening dyspnoea, cough and chest pain. This was on a background of weight loss, decreased appetite, mononeuritis multiplex, chronic eosinophilia and a single episode of a non-blanching rash. Investigations demonstrated a raised troponin and ischaemic changes on ECG, and she was therefore initially treated for a presumed myocardial infarction. However, her symptoms failed to improve with treatment for the acute coronary syndrome. A coronary angiogram revealed no significant flow-limiting disease, and further investigations yielded confirmation of raised eosinophils and a positive perinuclear antineutrophil cytoplasmic antibody test. An echocardiogram demonstrated a pericardial effusion, and subsequent cardiac magnetic resonance features were compatible with myopericarditis. In light of these findings, the patient was diagnosed with eosinophilic granulomatous with polyangiitis and commenced on high-dose intravenous methylprednisolone and cyclophosphamide. She made an excellent recovery and remains in remission on azathioprine and a tapering dose of corticosteroids.

Indexed as

Anti-Inflammatory AgentsCyclophosphamideEosinophilic GranulomaFemaleGranulomatosis with PolyangiitisHumansImmunosuppressive AgentsMethylprednisoloneMiddle AgedMyocarditisPericarditisAnti-Inflammatory AgentsCyclophosphamideImmunosuppressive AgentsMethylprednisolonepericardial diseasevasculitis

Identifiers

PMID31420437
PMCPMC6700583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.