Evidence map›Paper›PMID 31420345›Full record

ArticleApplied and environmental microbiology2019

Novel Probiotic Mechanisms of the Oral Bacterium

K Lee, A R Walker, B Chakraborty, J R Kaspar, M M Nascimento, R A Burne

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Streptococcus dentisani and Streptococcus mutans in dental biofilm of preschoolers with and without early childhood caries: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  3. A strain ofApplied and environmental microbiology · 2025
    Article
  4. Article
  5. A Strain ofbioRxiv : the preprint server for biology · 2024
    Article
  6. Review
  7. Catalase produced bymSphere · 2023
    Article
  8. Mechanism of Action ofAntibiotics (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Review
  11. Adjunctive role of Q10 withFrontiers in cellular and infection microbiology · 2023
    Article
  12. Application of a Bacillus subtilis Whole-Cell Biosensor (PMethods in molecular biology (Clifton, N.J.) · 2023
    Article
  13. Review
  14. Article
  15. Frontiers in microbiology · 2022
    Article
  16. Article
  17. Applied and environmental microbiology · 2021
    Article
  18. Article
  19. Anti-caries Streptococcus spp.: A potential preventive tool for special needs patients.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

K LeeDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.
A R WalkerDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.
B ChakrabortyDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.
J R KasparDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.ORCID 0000-0001-6901-5524
M M NascimentoDivision of Operative Dentistry, Department of Restorative Dental Sciences, College of Dentistry, University of Florida, Gainesville, Florida, USA.
R A BurneDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA rburne@dental.ufl.edu.ORCID 0000-0002-4234-0316
University of Florida · US

Funding

Comprehensive Training Program in Oral BiologyT90DE021990 · NIDCR · UNIVERSITY OF FLORIDA · PI Jose A Lemos · 2011 to 2026
$8.2M
Probiotics that moderate pH and antagonize pathogens to promote oral healthR01DE025832 · NIDCR · UNIVERSITY OF FLORIDA · PI BURNE, ROBERT A · 2016 to 2020
$3.4M
Oral alkali production and caries prevention in childrenK23DE023579 · NIDCR · UNIVERSITY OF FLORIDA · PI NASCIMENTO, MARCELLE M. · 2014 to 2018
$647k
Investigation of the probiotic mechanisms of action of Streptococcus A12F30DE028184 · NIDCR · UNIVERSITY OF FLORIDA · PI LEE, KYULIM · 2018 to 2019
$87k
NIDCR NIH HHS F30 DE028184NIDCR NIH HHS K23 DE023579NIDCR NIH HHS R01 DE025832NIDCR NIH HHS T90 DE021990
6 · The paper itself

Abstract

Health-associated biofilms in the oral cavity are composed of a diverse group of microbial species that can foster an environment that is less favorable for the outgrowth of dental caries pathogens, like

Indexed as

Anti-Infective AgentsAntimicrobial Cationic PeptidesBiofilmsColicinsDental CariesGene Expression Regulation, BacterialGene FusionGenomicsImmunityMicrobiotaMouthProbioticsStreptococcusStreptococcus mutansVirulenceAnti-Infective AgentsAntimicrobial Cationic PeptidesColicinsantimicrobial peptidesbiofilm ecologydental cariesinterspecies competitionoral microbiome

Identifiers

PMID31420345
PMCPMC6803316
OpenAlexW2969705864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.