Evidence map›Paper›PMID 31420335›Full record

ArticleApplied and environmental microbiology2019

Luminescent Nanosensors for Ratiometric Monitoring of Three-Dimensional Oxygen Gradients in Laboratory and Clinical Pseudomonas aeruginosa Biofilms.

Megan P Jewell, Anne A Galyean, J Kirk Harris, Edith T Zemanick, Kevin J Cash

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. pH-OBiofilm · 2026
    Article
  3. Review
  4. Oxygen microenvironments inMicrobiology (Reading, England) · 2025
    Article
  5. Review
  6. Sensor system for analysis of biofilm sensitivity to ampicillin.Applied microbiology and biotechnology · 2024
    Article
  7. Article
  8. Article
  9. The role of nanocomposites against biofilm infections in humans.Frontiers in cellular and infection microbiology · 2023
    Review
  10. Optical OmBio · 2022
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Megan P JewellChemical and Biological Engineering Department, Colorado School of Mines, Golden, Colorado, USA.
Anne A GalyeanChemical and Biological Engineering Department, Colorado School of Mines, Golden, Colorado, USA.
J Kirk HarrisDepartment of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Edith T ZemanickDepartment of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Kevin J CashChemical and Biological Engineering Department, Colorado School of Mines, Golden, Colorado, USA kcash@mines.edu.
Colorado School of Mines · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · US

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
ZEBRAFISH TRANSGENIC CORE - ROCKY MOUNTAIN NEUROLOGICAL DISORDERS CORE CENTERP30NS048154 · NINDS · UNIVERSITY OF COLORADO DENVER · PI RIBERA, ANGELES BADELL · 2004 to 2020
$10.1M
Neuronal Transdifferention in vivo: Mechanism and PotentialR01NS086839 · NINDS · UNIVERSITY OF COLORADO DENVER · PI RIBERA, ANGELES BADELL · 2014 to 2018
$1.7M
NCATS NIH HHS UL1 TR001082NINDS NIH HHS P30 NS048154NINDS NIH HHS R01 NS086839
6 · The paper itself

Abstract

Bacterial biofilms can form persistent infections on wounds and implanted medical devices and are associated with many chronic diseases, such as cystic fibrosis. These infections are medically difficult to treat, as biofilms are more resistant to antibiotic attack than their planktonic counterparts. An understanding of the spatial and temporal variation in the metabolism of biofilms is a critical component toward improved biofilm treatments. To this end, we developed oxygen-sensitive luminescent nanosensors to measure three-dimensional (3D) oxygen gradients, an application of which is demonstrated here with

Indexed as

Bacteriological TechniquesBiofilmsLuminescent MeasurementsOxygenPseudomonas aeruginosaPseudomonas InfectionsOxygenbiofilmsbiosensorscystic fibrosisnanosensorsoxygen sensing

Identifiers

PMID31420335
PMCPMC6805078
OpenAlexW2967272855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.