Observational studyBMC cardiovascular disorders2019
Evaluation of the autonomic nervous system by analysis of heart rate variability in the preterm infants.
Observational study in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 34 citations in OpenAlex.
- Cardiorespiratory measures shortly after extubation and extubation outcomes in extremely preterm infants.Pediatric research · 2023Trial
- Effects of E-cigarette and tobacco use on heart rate variability: a case-control study.Scientific reports · 2026Article
- Ameliorative Effect of Valeric Acid Against Psychophysiological Chronic Unpredictable Stress.Biomedicines · 2026Article
- Heart Rate Variability Nomogram Predicts Atrial Fibrillation in Patients with Moderate to High Burden of Premature Ventricular Complexes.Medicina (Kaunas, Lithuania) · 2026Article
- Music-based research in neonatal intensive care units requires guidelines grounded in developmental neurology and responsive to the individual needs of preterm infants.Frontiers in psychology · 2026Article
- The effect of music familiarity on preschoolers' heart rate during musical engagement: preliminary report.Frontiers in psychology · 2026Article
- Cardiorespiratory mechanisms triggered during music perception in preterm infants and adults.iScience · 2025Article
- Third-Trimester Development of Central Autonomic Network Connectivity Is Altered in an Extrauterine Environment.Neonatology · 2025Article
- Assessing Children's Autonomic Nervous System Activity During Structured Tasks: A Feasibility and Reliability Study in Ghana.Developmental psychobiology · 2024Article
- Heart rate variability measurement and influencing factors: Towards the standardization of methodology.Global cardiology science & practice · 2024Review
- Heart Rate Variability in Surgical Patients Experiencing Live Bedside Music; An Explorative Study.Applied psychophysiology and biofeedback · 2024Article
- Imbalance of Peripheral Temperature, Sympathovagal, and Cytokine Profile in Long COVID.Biology · 2023Article
- Comparing Full and Pre-Term Neonates' Heart Rate Variability in Rest Condition and during Spontaneous Interactions with Their Parents at Home.Healthcare (Basel, Switzerland) · 2023Article
- Comparison of oxygen supplementation in very preterm infants: Variations of oxygen saturation features and their application to hypoxemic episode based risk stratification.Frontiers in pediatrics · 2023Article
- Pilot study shows skin-to-skin care with parents improves heart rate variability in preterm infants in the neonatal intensive care unit.Frontiers in pediatrics · 2023Article
- Feasibility of Precision Medicine in Hypertension Management-Scope and Technological Aspects.Journal of personalized medicine · 2022Article
- Heart rate variability in children: methodological issues and clinical applications.Archivos de cardiologia de Mexico · 2022Article
- Characterisation of neonatal cardiac dynamics using ordinal partition network.Medical & biological engineering & computing · 2022Article
- Neonatal heart rate variability: a contemporary scoping review of analysis methods and clinical applications.BMJ open · 2021Article
- Interleukin-6 expression and its modulation by diacerein in a rat model of chronic stress induced cardiac dysfunction.Heliyon · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPremature infants may present with damage to the autonomic nervous system (ANS), which may be related to poorer neurological development. Among the techniques used to evaluate the ANS, heart rate variability (HRV) emerged as a simple, non-invasive, and easy to apply tool. The aim of the present study was to analyze and compare HRV in preterm infants at different times of hospitalization in order to verify the possible environmental relationships or clinical evolution with HRV.
methodsA longitudinal, prospective, and descriptive study with non-probabilistic sampling composed of 25 collections of preterm infants of HRV at two moments: moment I (within 15 days of birth) and moment II (after 45 days post-birth). The Polar V800 heart rate monitor was used with the Polar H10 cardiac transducer to collect HRV, which was collected in the supine position for 15 min. The HRV data were analyzed by the linear method in frequency domain and time domain and by the nonlinear method using Kubios HRV analysis software, version 3.0.2.
resultsThere was an increase in HRV values at moment II, these being statistically significant in the SD1, ApEn, and SampEn. Data related to increased sympathetic nervous system activity, parasympathetic nervous system activity, and increased index complexity.
conclusionsThe data demonstrate an increase in HRV values in premature infants at moment II, demonstrating a possible development in the maturation of the ANS during hospitalization.
trial registrationRBR-3x7gz8 retrospectively registered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.