Evidence map›Paper›PMID 31420006›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2019

Using neighborhood gray tone difference matrix texture features on dual time point PET/CT images to differentiate malignant from benign FDG-avid solitary pulmonary nodules.

Song Chen, Stephanie Harmon, Timothy Perk, Xuena Li, Meijie Chen, Yaming Li, Robert Jeraj

Open access · goldAbstract read
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Development of anQuantitative imaging in medicine and surgery · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Song ChenDepartment of Nuclear Medicine, The First Hospital of China Medical University, No.155 North Nanjing Street, Heping District, Shenyang City, Liaoning Province, 110001, People's Republic of China.
Stephanie HarmonDepartment of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, USA.
Timothy PerkDepartment of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, USA.
Xuena LiDepartment of Nuclear Medicine, The First Hospital of China Medical University, No.155 North Nanjing Street, Heping District, Shenyang City, Liaoning Province, 110001, People's Republic of China.
Meijie ChenDepartment of Nuclear Medicine, The First Hospital of China Medical University, No.155 North Nanjing Street, Heping District, Shenyang City, Liaoning Province, 110001, People's Republic of China.
Yaming LiDepartment of Nuclear Medicine, The First Hospital of China Medical University, No.155 North Nanjing Street, Heping District, Shenyang City, Liaoning Province, 110001, People's Republic of China. ymli2001@163.com.
Robert JerajDepartment of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, USA.
First Hospital of China Medical University · CNUniversity of Wisconsin–Madison · USChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLung cancer usually presents as a solitary pulmonary nodule (SPN) on diagnostic imaging during the early stages of the disease. Since the early diagnosis of lung cancer is very important for treatment, the accurate diagnosis of SPNs has much importance. The aim of this study was to evaluate the discriminant power of dual time point imaging (DTPI) PET/CT in the differentiation of malignant and benign FDG-avid solitary pulmonary nodules by using neighborhood gray-tone difference matrix (NGTDM) texture features.

methodsRetrospective analysis was carried out on 116 patients with SPNs (35 benign and 81 malignant) who had DTPI

resultsIn the training dataset, the AUCs of delayed busyness, delayed coarseness, early busyness, and early SUV

conclusionCompared to SUV

Indexed as

AgedFemaleFluorodeoxyglucose F18HumansLung NeoplasmsMaleMiddle AgedPositron Emission Tomography Computed TomographyRadiopharmaceuticalsSensitivity and SpecificitySolitary Pulmonary NoduleFluorodeoxyglucose F18RadiopharmaceuticalsFluorodeoxyglucose F18Lung neoplasmsPositron emission tomography computed tomographySolitary pulmonary nodules

Identifiers

PMID31420006
PMCPMC6697997
OpenAlexW2968063452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.