Evidence map›Paper›PMID 31419959›Full record

ArticleBMC neurology2019

Intracranial mechanical thrombectomy of large vessel occlusions in the posterior circulation using SAVE.

Volker Maus, Hanna Styczen, Jan Liman, Ilko Maier, Alex Brehm, Ioannis Tsogkas, Marios-Nikos Psychogios

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  4. Article
  5. Predictors and outcomes of first pass efficacy in posterior circulation strokes: Insights from STAR collaboration.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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  9. Thrombectomy for distal medium vessel occlusion with a new generation of Stentretriever (Tigertriever 13).Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Volker MausDepartment of Diagnostic and Interventional Neuroradiology, University Medical Center Goettingen, Goettingen, Germany. volker.maus@kk-bochum.de.ORCID http://orcid.org/0000-0001-5097-2631
Hanna StyczenDepartment of Diagnostic and Interventional Neuroradiology, University Medical Center Goettingen, Goettingen, Germany.
Jan LimanDepartment of Neurology, University Medical Center Goettingen, Goettingen, Germany.
Ilko MaierDepartment of Neurology, University Medical Center Goettingen, Goettingen, Germany.
Alex BrehmDepartment of Diagnostic and Interventional Neuroradiology, University Medical Center Goettingen, Goettingen, Germany.
Ioannis TsogkasDepartment of Diagnostic and Interventional Neuroradiology, University Medical Center Goettingen, Goettingen, Germany.
Marios-Nikos PsychogiosDepartment of Diagnostic and Interventional Neuroradiology, University Medical Center Goettingen, Goettingen, Germany.
Universitätsklinikum Knappschaftskrankenhaus Bochum · DEUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical thrombectomy (MT) using stent retriever assisted vacuum-locked extraction (SAVE) is a promising method for anterior circulation strokes. We present our experience with SAVE for large vessel occlusions (LVO) of the posterior circulation.

methodsWe retrospectively analyzed 66 consecutive MT patients suffering from LVO of the posterior circulation. Primary endpoints were first-pass and overall complete/near complete reperfusion, defined as a modified thrombolysis in cerebral infarction (mTICI) score of 2c and 3. Secondary endpoints contained number of passes, time interval from groin puncture to reperfusion and rate of postinterventional symptomatic intracranial hemorrhage (sICH).

resultsMedian age was 75 years (interquartile range (IQR) 54-81 years). Baseline median National Institutes of Health stroke scale (NIHSS) was 13 (IQR 8-21). Fifty-five (83%) patients had LVO of the basilar artery and 11 (17%) of the posterior cerebral artery. Eighteen (27%) patients were treated with SAVE and 21 (32%) with aspiration only. First pass mTICI2c or 3 and overall mTICI2c or 3 were documented in 11/18 (61%) and 14/18 (78%) with SAVE and in 4/21 (19%) and 13/21 (33%) with aspiration only. Median attempt was 1 (IQR 1-2) with SAVE and 2 (IQR 1-4) with aspiration (p = 0.0249). Median groin to reperfusion time did not differ significantly between groups. The rate of sICH was 5% without any complications in the SAVE cohort.

conclusionMechanical thrombectomy of posterior large vessel occlusions with SAVE is feasible, safe, and effective with high rates of near-complete and complete reperfusion.

Indexed as

AgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesStentsStrokeThrombectomyTreatment OutcomeAcute ischemic strokeMechanical thrombectomyPosterior circulation strokeSAVE

Identifiers

PMID31419959
PMCPMC6696671
OpenAlexW2967027042

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.