ArticleAmerican heart journal2019
Rationale and design of a nurse-led intervention to extend the HIV treatment cascade for cardiovascular disease prevention trial (EXTRA-CVD).
Article in American heart journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04661813 (Assess and Adapt to the Impact of COVID-19 on CVD Self-Management and Prevention Care in Adults Living With HIV), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assess and Adapt to the Impact of COVID-19 on CVD Self-Management and Prevention Care in Adults Living With HIV
Who cites it
15 citing papers in PubMed.
- Nurse-Led Strategy to Improve Blood Pressure and Cholesterol Level Among People With HIV: A Randomized Clinical Trial.JAMA network open · 2024Trial
- The influence of healthcare financing on cardiovascular disease prevention in people living with HIV.BMC public health · 2020Trial
- Mental Health Stressors of the COVID-19 Pandemic Negatively Affect Self-Management of Comorbid Cardiovascular Disease Among Persons Living With HIV in the United States: A Qualitative Study.The Journal of the Association of Nurses in AIDS Care : JANACTrial
- Reciprocal innovation in implementation science and global health: reflections from the EXTRA-CVD (extending the HIV treatment cascade for cardiovascular disease prevention) study.BMC global and public health · 2026Review
- Implementation strategies to integrate HIV and hypertension care in Kampala and Wakiso districts, Uganda: study protocol for a stepped wedge cluster randomized trial (PULESA-Uganda).BMC health services research · 2025Article
- Lifting all boats: strategies to promote equitable bidirectional research training opportunities to enhance global health reciprocal innovation.BMJ global health · 2023Article
- The impact of COVID-19 on cardiovascular health behaviors in people living with HIV.AIDS care · 2023Article
- Understanding constraints on integrated care for people with HIV and multimorbid cardiovascular conditions: an application of the Theoretical Domains Framework.Implementation science communications · 2021Article
- Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?Open forum infectious diseases · 2020Article
- Why Do People Living with HIV Adhere to Antiretroviral Therapy and Not Comorbid Cardiovascular Disease Medications? A Qualitative Inquiry.Patient preference and adherence · 2020Article
- Enhancing Cardiovascular Health in Southeastern United States for Underrepresented Racial and Ethnic Minorities With HIV: A Qualitative Inquiry Using the Health Belief Model.The Journal of the Association of Nurses in AIDS Care : JANACArticle
- Use of a human-centered design approach to adapt a nurse-led cardiovascular disease prevention intervention in HIV clinics.Progress in cardiovascular diseasesArticle
- Prevention as treatment: A bold vision for improving the cardiovascular health of people living with HIV.Progress in cardiovascular diseasesArticle
- Prevention of cardiovascular disease for historically marginalized racial and ethnic groups living with HIV: A narrative review of the literature.Progress in cardiovascular diseasesReview
- ImPlementation REsearCh to DEvelop Interventions for People Living with HIV (the PRECluDE consortium): Combatting chronic disease comorbidities in HIV populations through implementation research.Progress in cardiovascular diseasesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
Persons living with human immunodeficiency virus (PLHIV) are at increased risk of atherosclerotic cardiovascular disease (ASCVD). In spite of this, uptake of evidence-based clinical interventions for ASCVD risk reduction in the HIV clinic setting is sub-optimal.
methodsEXTRA-CVD is a 12-month randomized clinical effectiveness trial that will assess the efficacy of a multi-component nurse-led intervention in reducing ASCVD risk among PLHIV. Three hundred high ASCVD risk PLHIV across three sites will be randomized 1:1 to usual care with generic prevention education or the study intervention. The study intervention will consist of four evidence-based components: (1) nurse-led care coordination, (2) nurse-managed medication protocols and adherence support (3) home BP monitoring, and (4) electronic health records support tools. The primary outcome will be change in systolic blood pressure and secondary outcome will be change in non-HDL cholesterol over the course of the intervention. Tertiary outcomes will include change in the proportion of participants in the following extended cascade categories: (1) appropriately diagnosed with hypertension and hyperlipidemia (2) appropriately managed; (3) at treatment goal (systolic blood pressure <130 mm Hg and non-HDL cholesterol < National Lipid Association targets).
conclusionsThe EXTRA-CVD trial will provide evidence appraising the potential impact of nurse-led interventions in reducing ASCVD risk among PLHIV, an essential extension of the HIV care continuum beyond HIV viral suppression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.