Evidence map›Paper›PMID 31419087›Full record

ArticleJournal of cachexia, sarcopenia and muscle2019

The Copenhagen Sarcopenia Study: lean mass, strength, power, and physical function in a Danish cohort aged 20-93 years.

Charlotte Suetta, Bryan Haddock, Julian Alcazar, Tim Noerst, Ole M Hansen, Helle Ludvig, Rikke Stefan Kamper, Peter Schnohr, Eva Prescott, Lars L Andersen and 5 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of cachexia, sarcopenia and muscle, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04515342 (Sarcopenia, Fall and Osteoporosis in Patients With Chronic Kidney Disease), which is not on this map. Cited by 145 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 7 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04515342 unknown statusnot on this mapstarted 2021, after this paper: background citation

Sarcopenia, Fall and Osteoporosis in Patients With Chronic Kidney Disease

TypeobservationalSponsorHerlev HospitalRan2021 to 2026Enrolled140ConditionsSarcopenia, Chronic Kidney Diseases, OsteoporosisArmsDXA, Muscle strength and function assessment, Blood samples
3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 7 syntheses or guidelines pooled it, 285 citations in OpenAlex.

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  12. Changes in spinal bone density, back muscle size, and visceral adipose tissue and their interaction following a multi-component exercise program in older men: secondary analysis of an 18-month randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Trial
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  16. Muscle fibre denervation in ageing.Clinical science (London, England : 1979) · 2026
    Review
  17. The kidney failure risk equation in people with CKD and multimorbidity: the effect of competing mortality risks.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Observational
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85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Charlotte SuettaDepartment of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet-Glostrup, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0001-8063-6508
Bryan HaddockDepartment of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet-Glostrup, Copenhagen University Hospital, Copenhagen, Denmark.
Julian AlcazarGeriatric Research Unit, Geriatric Department, Bispebjerg-Frederiksberg University Hospital, Copenhagen, Denmark.
Tim NoerstDepartment of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet-Glostrup, Copenhagen University Hospital, Copenhagen, Denmark.
Ole M HansenDepartment of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet-Glostrup, Copenhagen University Hospital, Copenhagen, Denmark.
Helle LudvigDepartment of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet-Glostrup, Copenhagen University Hospital, Copenhagen, Denmark.
Rikke Stefan KamperDepartment of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet-Glostrup, Copenhagen University Hospital, Copenhagen, Denmark.
Peter SchnohrCopenhagen City Heart Study, Bispebjerg-Frederiksberg University Hospital, Copenhagen, Denmark.
Eva PrescottCopenhagen City Heart Study, Bispebjerg-Frederiksberg University Hospital, Copenhagen, Denmark.
Lars L AndersenNational Research Centre for the Working Environment, Copenhagen, Denmark.
Ulrik FrandsenDepartment of Sports Science and Clinical Biomechanics, Research Unit for Muscle Physiology and Biomechanics, University of Southern Denmark, Odense, Denmark.
Per AagaardDepartment of Sports Science and Clinical Biomechanics, Research Unit for Muscle Physiology and Biomechanics, University of Southern Denmark, Odense, Denmark.
Jens BülowDepartment of Clinical Physiology and Nuclear Medicine, Bispebjerg-Frederiksberg University Hospital, Copenhagen, Denmark.
Peter HovindDepartment of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet-Glostrup, Copenhagen University Hospital, Copenhagen, Denmark.
Lene SimonsenDepartment of Clinical Physiology and Nuclear Medicine, Bispebjerg-Frederiksberg University Hospital, Copenhagen, Denmark.
Frederiksberg Hospital · DKGlostrup Hospital · DKUniversity of Southern Denmark · DKNational Research Centre for the Working Environment · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite no international consensus on the diagnostic criteria for sarcopenia, low lean mass, muscle strength, and physical function are important risk factors for disability, frailty, and mortality in older individuals, as well as in a wide range of patients with muscle loss. Here, we provide a population-based reference material of total and regional lean body mass, muscle strength/power parameters, and physical function in a healthy cohort of Danish men and women across the lifespan.

methodsVolunteers aged 20-93 years from the Copenhagen City Heart Study were invited to establish a Danish reference material (Copenhagen Sarcopenia Study) on lean mass characteristics [appendicular lean mass (ALM), iDXA, GE Lunar], muscle function [handgrip strength (HGS), Jamar dynamometer and leg extension power (LEP), Nottingham Power Rig], and physical function [30 s sit-to-stand test (STS), 10-m maximal and habitual gait speed (GS)].

resultsA total of 1305 participants [729 women (age: 56.4 ± 18.9 years, height: 1.66 ± 0.01 m, body mass index: 24.6 ± 4.3 kg/m

Indexed as

AdultAgedAged, 80 and overBody CompositionCohort StudiesCross-Sectional StudiesDenmarkFemaleHand StrengthHumansLegLongevityMiddle AgedProspective StudiesSarcopeniaYoung AdultBody compositionDXAHandgrip strengthLean massLeg powerSarcopenia

Identifiers

PMID31419087
PMCPMC6903448
OpenAlexW2968204045

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.