Evidence map›Paper›PMID 31418686›Full record

ArticleeLife2019

Epigenetic silencing of a multifunctional plant stress regulator.

Mark Zander, Björn C Willige, Yupeng He, Thu A Nguyen, Amber E Langford, Ramlah Nehring, Elizabeth Howell, Robert McGrath, Anna Bartlett, Rosa Castanon and 9 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Review
  3. TheProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. PIF transcription factors-versatile plant epigenome landscapers.Frontiers in epigenetics and epigenomics · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. AtINO80 represses photomorphogenesis by modulating nucleosome density and H2A.Z incorporation in light-related genes.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Review
  18. Article
  19. H2A Variants inPlant communications · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Mark ZanderPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0001-8643-1407
Björn C WilligePlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0003-4275-5826
Yupeng HeGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0001-9313-614X
Thu A NguyenPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Amber E LangfordPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0001-9573-9905
Ramlah NehringPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Elizabeth HowellPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Robert McGrathDepartment of Biology, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0002-4002-1522
Anna BartlettGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Rosa CastanonGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Joseph R NeryGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Huaming ChenGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0001-5289-7882
Zhuzhu ZhangGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Florian JupeGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0001-5741-4931
Anna StepanovaPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Robert J SchmitzPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0001-7538-6663
Mathew G LewseyPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0002-2631-4337
Joanne ChoryPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Joseph R EckerPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0001-5799-5895
Salk Institute for Biological Studies · USUniversity of Pennsylvania · US

Funding

Mechanisms Controlling Hormone-Mediated Plant Growth in Response to the EnvironmentR35GM122604 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CHORY, JOANNE · 2017 to 2021
$2.0M
Department of Energy, Office of Basic Energy Sciences DE-FG02-04ER15517Deutsche Forschungsgemeinschaft Za-730/1-1EU 7th Framework Programme EU Marie Curie FP7 International Outgoing Fellowship: 252475EU Marie Curie FP7 International Outgoing Fellowship 252475Gordon and Betty Moore Foundation GBMF3034Human Frontier Science Program LT000222/2013-LNational Science Foundation MCB-1024999NIGMS NIH HHS R35 GM122604NIH HHS 5R35 GM122604U.S. Department of Energy DOE FG02 04ER15517
6 · The paper itself

Abstract

The central regulator of the ethylene (ET) signaling pathway, which controls a plethora of developmental programs and responses to environmental cues in plants, is ETHYLENE-INSENSITIVE2 (EIN2). Here we identify a chromatin-dependent regulatory mechanism at

Indexed as

Epigenesis, GeneticGene Expression Regulation, PlantArabidopsisArabidopsis ProteinsEthylenesNuclear ProteinsReceptors, Cell SurfaceSignal TransductionTranscription FactorsArabidopsis ProteinsAT4G38495 protein, ArabidopsisEIN2 protein, ArabidopsisethyleneEthylenesNuclear ProteinsReceptors, Cell SurfaceREF6 protein, ArabidopsisTranscription FactorsA. thalianachromatin remodelingethylenegeneticsgenomicshistone demethylationplant biologyplant epigenomics

Identifiers

PMID31418686
PMCPMC6739875
OpenAlexW2967698725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.