ArticleCurrent Alzheimer research2019
Increased Prevalence of Vestibular Loss in Mild Cognitive Impairment and Alzheimer's Disease.
Article in Current Alzheimer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- Mechanistic research on the vestibular-hippocampal pathway in neurodegenerative diseases: an integrative perspective from molecular to behavioral levels.Frontiers in neuroscience · 2026Review
- The impact of bilateral vestibulopathy on quality of life: data from the Antwerp University Hospital registry.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Dual task reactive balance control in older adults with mild cognitive impairment: does the cognitive task domain make a difference?Journal of neurophysiology · 2025Article
- Vestibular dysfunction: a hidden risk factor for Alzheimer's disease.Journal of neurology · 2025Article
- Vestibular-evoked myogenic potential abnormalities in Parkinson's disease with freezing of gait.Journal of neurology · 2024Article
- Vestibular dysfunction and its association with cognitive impairment and dementia.Frontiers in neuroscience · 2024Review
- Multidimensional relationships between sensory perception and cognitive aging.Frontiers in aging neuroscience · 2024Article
- Cerebello-cortical functional connectivity may regulate reactive balance control in older adults with mild cognitive impairment.Frontiers in neurology · 2023Article
- Vestibular cognition assessment system: Tablet-based computerized visuospatial abilities test battery.Frontiers in psychology · 2023Article
- Research progress on vestibular dysfunction and visual-spatial cognition in patients with Alzheimer's disease.Frontiers in aging neuroscience · 2023Review
- Vestibular therapy to reduce falls in people with Alzheimer's disease: study protocol for a pilot randomized controlled trial.Pilot and feasibility studies · 2022Article
- An unbiased algorithm for objective separation of Alzheimer's, Alzheimer's mixed with cerebrovascular symptomology, and healthy controls from one another using electrovestibulography (EVestG).Medical & biological engineering & computing · 2022Article
- Hearing loss versus vestibular loss as contributors to cognitive dysfunction.Journal of neurology · 2022Review
- Linking cognitive functioning and postural balance control through virtual reality environmental manipulations.Frontiers in aging neuroscience · 2022Article
- Sport as a Factor in Improving Visual Spatial Cognitive Deficits in Patients with Hearing Loss and Chronic Vestibular Deficit.Audiology research · 2021Article
- Association between vestibular function and rotational spatial orientation perception in older adults.Journal of vestibular research : equilibrium & orientation · 2021Article
- Aging, Vestibular Function, and Balance: Proceedings of a National Institute on Aging/National Institute on Deafness and Other Communication Disorders Workshop.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Electroacupuncture Improves Cognitive Function in Senescence-Accelerated P8 (SAMP8) Mice via the NLRP3/Caspase-1 Pathway.Neural plasticity · 2020Article
- The Growing Evidence for the Importance of the Otoliths in Spatial Memory.Frontiers in neural circuits · 2019Review
- Getting LOST: A conceptual framework for supporting and enhancing spatial navigation in aging.Wiley interdisciplinary reviews. Cognitive scienceReview
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND/
aimsRecent evidence has shown that Alzheimer's Disease (AD) patients have reduced vestibular function relative to healthy controls. In this study, we evaluated whether patients with Mild Cognitive Impairment (MCI) also have reduced vestibular function relative to controls, and compared the level of vestibular impairment between MCI and AD patients.
methodsVestibular physiologic function was assessed in 77 patients (26 MCI, 51 AD) and 295 matched controls using 3 clinical vestibular tests. The association between vestibular loss and cognitive impairment was evaluated using conditional logistic regression models.
resultsIndividuals with vestibular impairment had a 3 to 4-fold increased odds of being in the MCI vs. control group (p-values < 0.05). MCI patients had a level of vestibular impairment that was intermediate between controls and AD.
conclusionThese findings suggest a dose-response relationship between vestibular loss and cognitive status, and support the hypothesis that vestibular loss contributes to cognitive decline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.