Evidence map›Paper›PMID 31418553›Full record

ArticleACS nano2019

Modifying Membrane Morphology and Interactions with DNA Origami Clathrin-Mimic Networks.

Céline M A Journot, Vivek Ramakrishna, Mark I Wallace, Andrew J Turberfield

Open access · hybridAbstract read
In one paragraph

Article in ACS nano, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 61 citations in OpenAlex.

  1. Membrane-Associated Biomolecules for Synthetic Cell Signalling.Chembiochem : a European journal of chemical biology · 2026
    Review
  2. Article
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  9. DNA Origami Vesicle Sensors with Triggered Single-Molecule Cargo Transfer.Angewandte Chemie (International ed. in English) · 2024
    Article
  10. Review
  11. Article
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  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Dynamics of DNA Origami Lattices.Bioconjugate chemistry · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Céline M A JournotDepartment of Physics, Clarendon Laboratory , University of Oxford , Parks Road , Oxford OX1 3PU , United Kingdom.
Vivek RamakrishnaDepartment of Chemistry , King's College London , Britannia House, 7 Trinity Street , London SE1 1DB , United Kingdom.
Mark I WallaceDepartment of Chemistry , King's College London , Britannia House, 7 Trinity Street , London SE1 1DB , United Kingdom.ORCID 0000-0002-5692-8313
Andrew J TurberfieldDepartment of Physics, Clarendon Laboratory , University of Oxford , Parks Road , Oxford OX1 3PU , United Kingdom.ORCID 0000-0002-3876-0190
King's College London · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the triggered assembly of a bioinspired DNA origami meshwork on a lipid membrane. DNA triskelia, three-armed DNA origami nanostructures inspired by the membrane-modifying protein clathrin, are bound to lipid mono- and bilayers using cholesterol anchors. Polymerization of triskelia, triggered by the addition of DNA staples, links triskelion arms to form a mesh. Using transmission electron microscopy, we observe nanoscale local deformation of a lipid monolayer induced by triskelion polymerization that is reminiscent of the formation of clathrin-coated pits. We also show that the polymerization of triskelia bound to lipid bilayers modifies interactions between them, inhibiting the formation of a synapse between giant unilamellar vesicles and a supported lipid bilayer.

Indexed as

Membranes, ArtificialNucleic Acid ConformationClathrinDNALipid BilayersUnilamellar LiposomesClathrinDNALipid BilayersMembranes, ArtificialUnilamellar Liposomesbiomimeticclathrin-inspired nanostructureDNA origamimembrane interactionnanotechnology

Identifiers

PMID31418553
PMCPMC6764109
OpenAlexW2967158224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.