SynthesisSleep & breathing = Schlaf & Atmung2020
Hypoglossal nerve stimulation long-term clinical outcomes: a systematic review and meta-analysis.
Synthesis in Sleep & breathing = Schlaf & Atmung, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Patient-reported outcomes with hypoglossal nerve stimulation for treatment of obstructive sleep apnea: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Pooled it
- Upper airway stimulation vs other upper airway surgical procedures for OSA: a meta-analysis.Sleep & breathing = Schlaf & Atmung · 2022Pooled it
- Snoring increases the development of coronary artery disease: a systematic review with meta-analysis of observational studies.Sleep & breathing = Schlaf & Atmung · 2021Pooled it
- Electrical stimulation as a therapeutic approach in obstructive sleep apnea - a meta-analysis.Sleep & breathing = Schlaf & Atmung · 2021Pooled it
- Different barbed pharyngoplasty techniques for retropalatal collapse in obstructive sleep apnea patients: a systematic review.Sleep & breathing = Schlaf & Atmung · 2020Pooled it
- Dextrose prolotherapy versus low level laser therapy in the treatment of patients with obstructive sleep apnea syndrome; a randomized controlled trial.Sleep & breathing = Schlaf & Atmung · 2025Trial
- Sleep-Related Breathing Disorders: A Comprehensive Review of Surgical Innovations and Evolving Technologies.Healthcare (Basel, Switzerland) · 2026Review
- Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis on Responder-Based Outcomes and Between-Study Heterogeneity.Journal of clinical medicine · 2026Review
- Effect of Malocclusion on Response to Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea.Laryngoscope investigative otolaryngology · 2026Article
- Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024).World journal of otorhinolaryngology - head and neck surgery · 2026Article
- Therapeutic Efficacy of Endoscope-Guided Coblation for Tongue Base Reduction as Part of Multilevel Surgery in Moderate to Severe OSA Patients.World journal of otorhinolaryngology - head and neck surgery · 2026Article
- Hypoglossal nerve stimulation in a pig model for evaluation of genioglossus muscle force with different stimulation parameters.Scientific reports · 2026Article
- Impact of Postoperative Weight Changes on Hypoglossal Nerve Stimulation Success for Obstructive Sleep Apnea.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Role of Free Radicals in the Pathophysiology of OSA: A Narrative Review of a Double-Edged Sword.Journal of clinical medicine · 2025Review
- Backscattered Ultrasonographic Imaging of the Tongue and Outcome in Hypoglossal Nerve Stimulation.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- The activation, clinical course, and clinical outcome of using an unconventional electrode configuration in a patient newly implanted with Inspire® therapy: a case report.Frontiers in medicine · 2025Article
- Transoral Robotic Surgery Versus Hypoglossal Nerve Stimulation for OSA: A Cost Analysis Study.The Laryngoscope · 2025Article
- Video-assisted thoracoscopic surgery retrieval of a migrated unilateral hypoglossal nerve stimulator sensor lead.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- COJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Adverse Events with Hypoglossal Nerve Stimulation in the Treatment of Obstructive Sleep Apnea-A Systematic Review of Clinical Trials and Real-World Data.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo perform a systematic review and meta-analysis for studies evaluating hypoglossal nerve stimulation (HNS) clinical outcomes in the treatment of moderate to severe obstructive sleep apnea (OSA).
methodsTwo authors conducted a literature search to identify prospective studies in PubMed/MEDLINE, Google Scholar, and Cochrane Library databases. The last search was performed on November 17, 2018.
resultsA total of 350 patients (median age 54.3 (IQR 53-56.25) years, BMI 29.8 (IQR 28.8-31.6) kg/m
conclusionHNS has obtained a high surgical success rate with reasonable long-term complication rate related to the device implanted. The procedure represents an effective and safe surgical treatment for moderate-severe OSA in selected adult patients who had difficulty accepting or adhering to CPAP treatment.
Indexed as
Identifiers
31418162What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.