Evidence map›Paper›PMID 31418100›Full record

ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2019

Epidemiology of invasive meningococcal disease in Greece, 2006-2016.

Anastasia Flountzi, Theano Georgakopoulou, Sooria Balasegaram, Konstantinos Kesanopoulos, Athanasia Xirogianni, Anastasia Papandreou, Georgina Tzanakaki, Members of the Hellenic network for Invasive meningococcal disease

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. First report of meningococcal ciprofloxacin resistance in Greece due to invasive isolates of the sequence type ST-3129.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anastasia FlountziEuropean Programme for Public Health Microbiology Training (EUPHEM), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Theano GeorgakopoulouDepartment of Epidemiological Surveillance and Intervention of the National Public Health Organization (NPHO), Athens, Greece.
Sooria BalasegaramNational Infection Service, Public Health England, London, UK.
Konstantinos KesanopoulosNational Meningitis Reference Laboratory, Department of Public Health Policy, School of Public Health, University of West Attica, 196, Alexandras Avenue, Athens, Greece.
Athanasia XirogianniNational Meningitis Reference Laboratory, Department of Public Health Policy, School of Public Health, University of West Attica, 196, Alexandras Avenue, Athens, Greece.
Anastasia PapandreouNational Meningitis Reference Laboratory, Department of Public Health Policy, School of Public Health, University of West Attica, 196, Alexandras Avenue, Athens, Greece.
Georgina TzanakakiNational Meningitis Reference Laboratory, Department of Public Health Policy, School of Public Health, University of West Attica, 196, Alexandras Avenue, Athens, Greece. gtzanakaki@esdy.edu.gr.
Members of the Hellenic network for Invasive meningococcal disease

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study describes the epidemiology of invasive meningococcal disease (IMD) in Greece for the period 2006-2016. Combined data from notified and laboratory-confirmed IMD cases were obtained from the two involved National Centres (Epidemiology and Reference Laboratory). Laboratory identification and typing was carried out by both conventional (culture) and molecular methods (PCR, MLST, PorA, and FetA typing). A total of 796 IMD cases were notified; of those, 720 (91%) were laboratory confirmed. Overall, a decline on the annual incidence of confirmed cases was observed, ranging from 0.91 (2006) to 0.47 (2016) /100,000. A similar trend was observed in most age groups especially in children 0-4 years (7.7 to 2.9/100,000), with the exception of an increase in the incidence rate in adults > 20 years (0.21 to 0.32/100,000). The overall case fatality rate was 6.5% (52/796), annual range 2-13%. Among 658 strains which were typed by sero/genogroup, 80% were identified as MenB (annual range 65-92%); however, a decline was observed in MenB incidence from 5.3 (2006) to 2.7 (2016), among infants and toddlers, while MenW (1%), MenY (2%), and MenA (1%) remained low. During the 11 years, the annual incidence of IMD declined by 50%, especially in the 0-4-year age group, due mainly to MenB. Continuous surveillance of IMD is important for the development of future vaccination and public health policies.

Indexed as

Age FactorsAnti-Bacterial AgentsBacterial ProteinsClinical Laboratory TechniquesEpidemiological MonitoringGenotypeGreeceHumansIncidenceMeningococcal InfectionsMicrobial Sensitivity TestsNeisseria meningitidisSerogroupAnti-Bacterial AgentsBacterial ProteinsAntimicrobial susceptibilityClonal complexEpidemiologyfetAInvasive meningococcal disease (IMD)porA

Identifiers

PMID31418100

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.