ArticleMikrochimica acta2019
Laser-induced breakdown spectroscopy as a novel readout method for nanoparticle-based immunoassays.
Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 23 citations in OpenAlex.
- Laser-induced breakdown spectroscopy as a readout method for immunocytochemistry with upconversion nanoparticles.Mikrochimica acta · 2021Article
- Stability improvement for dried droplet pretreatment by suppression of coffee ring effect using electrochemical anodized nanoporous tin dioxide substrate.Mikrochimica acta · 2020Article
- Detection of E. coli labeled with metal-conjugated antibodies using lateral-flow assay and laser-induced breakdown spectroscopy.Analytical and bioanalytical chemistry · 2020Article
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7 authors at 2 institutions in 1 country.
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Abstract
Laser-induced breakdown spectroscopy (LIBS) was examined as a novel method for readout of microtiter plate immunoassays involving nanoparticles (NP). The so-called Tag-LIBS technique is a sensitive method for the detection of specific biomarkers. It was applied to the determination of NP labels using nanosecond ablation sampling. The NP labels were examined from the bottom of a standard 96-well microtiter plate. Thanks to the flexibility of LIBS instrumentation, both the plasma emission collection and the focusing optics arrangements can be collinearly arranged. The experiments showed that silver NPs and gold NPs can be readily quantified on the bottom of the microtiter plate. Utilizing this technique, a sandwich immunoassay for human serum albumin using streptavidin-coated AgNP labels was developed. The assay has a 10 ng·mL
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