Evidence map›Paper›PMID 31418062›Full record

ReviewPediatric nephrology (Berlin, Germany)2020

Should we abandon GFR in the decision to initiate chronic dialysis?

Evgenia Preka, Lesley Rees

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Validation of Patient-Reported Outcome Measure in Pediatric CKD (PRO-Kid).Clinical journal of the American Society of Nephrology : CJASN · 2024
    Article
  5. Review
  6. Think Twice before Postponing Chronic Dialysis in Children.Journal of the American Society of Nephrology : JASN · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Evgenia PrekaDepartment of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS foundation Trust, Great Ormond Street, London, WC1N 3JH, UK. evgenia.preka@gmail.com.ORCID 0000-0001-7130-0439
Lesley ReesDepartment of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS foundation Trust, Great Ormond Street, London, WC1N 3JH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The best time to start chronic dialysis during the course of CKD stage 5 is controversial. The first randomised control trial of dialysis initiation either in early or late CKD stage 5 in adults (IDEAL study), and 3 studies from the two largest paediatric registries, the U.S. Renal Data System (USRDS) and the European Society of Paediatric Nephrology (ESPN) Registry, have now provided us with evidence to guide us in this important decision-making process. The message 'no benefit from early start of dialysis' is the conclusion from all four studies. However, what are the limitations of these studies? Can GFR be assessed at CKD stages 4 and 5? What are the factors used to assess the benefit of early or late start? These issues are discussed in this review.

Indexed as

Decision MakingAdultChildFemaleGlomerular Filtration RateHumansInfant, NewbornKidney Failure, ChronicMalePractice Guidelines as TopicRegistriesRenal DialysisTime-to-TreatmentEnd-stage kidney diseaseGFRRenal replacement therapyTiming of dialysis initiation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.