Evidence map›Paper›PMID 31417766›Full record

ArticleRoyal Society open science2019

Reverse vaccinology and subtractive genomics reveal new therapeutic targets against

Thaís Cristina Vilela Rodrigues, Arun Kumar Jaiswal, Alissa de Sarom, Letícia de Castro Oliveira, Carlo José Freire Oliveira, Preetam Ghosh, Sandeep Tiwari, Fábio Malcher Miranda, Leandro de Jesus Benevides, Vasco Ariston de Carvalho Azevedo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Royal Society open science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 47 citations in OpenAlex.

  1. Pangenomics insights of enterococcus faecium human isolates and identification of novel therapeutic targets by in silico subtractive genomics.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Article
  3. Article
  4. Design of a Multi-Epitope Vaccine againstJournal of fungi (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Comparative Genomics ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Article
  10. Insights into theAntibiotics (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Reverse vaccinology and subtractive genomics approaches for identifying common therapeutics againstThe journal of venomous animals and toxins including tropical diseases · 2021
    Article
  17. Article
  18. Review
  19. Article
  20. Frontiers in genetics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Thaís Cristina Vilela RodriguesDepartment of Microbiology, Immunology and Parasitology, Federal University of Triângulo Mineiro, Minas Gerais, Brazil.ORCID 0000-0002-2048-5522
Arun Kumar JaiswalDepartment of Microbiology, Immunology and Parasitology, Federal University of Triângulo Mineiro, Minas Gerais, Brazil.
Alissa de SaromDepartment of Microbiology, Immunology and Parasitology, Federal University of Triângulo Mineiro, Minas Gerais, Brazil.ORCID 0000-0002-3146-7784
Letícia de Castro OliveiraDepartment of Microbiology, Immunology and Parasitology, Federal University of Triângulo Mineiro, Minas Gerais, Brazil.ORCID 0000-0002-2036-4456
Carlo José Freire OliveiraDepartment of Microbiology, Immunology and Parasitology, Federal University of Triângulo Mineiro, Minas Gerais, Brazil.
Preetam GhoshDepartment of Computer Science, Virginia Commonwealth University, Richmond, VA 23284, USA.ORCID 0000-0003-3880-5886
Sandeep TiwariDepartment of Genetics, Ecology and Evolution, Federal University of Minas Gerais, Minas Gerais, Brazil.ORCID 0000-0002-8554-1660
Fábio Malcher MirandaDepartment of Genetics, Ecology and Evolution, Federal University of Minas Gerais, Minas Gerais, Brazil.ORCID 0000-0002-6823-5995
Leandro de Jesus BenevidesBioinformatics Laboratory - LABINFO, National Laboratory of Scientific Computation - LNCC/MCTI, Rio de Janeiro, Brazil.
Vasco Ariston de Carvalho AzevedoDepartment of Genetics, Ecology and Evolution, Federal University of Minas Gerais, Minas Gerais, Brazil.
Siomar de Castro SoaresDepartment of Microbiology, Immunology and Parasitology, Federal University of Triângulo Mineiro, Minas Gerais, Brazil.
Universidade Federal de Minas Gerais · BRUniversidade Federal do Triângulo Mineiro · BRLaboratório Nacional de Computação Científica · BRVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pneumonia is an infectious disease caused by bacteria, viruses or fungi that results in millions of deaths globally. Despite the existence of prophylactic methods against some of the major pathogens of the disease, there is no efficient prophylaxis against atypical agents such as

Indexed as

bioinformaticsgenomicmolecular dockingMycoplasma pneumoniaepneumoniavaccinology

Identifiers

PMID31417766
PMCPMC6689572
OpenAlexW2965753825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.