Evidence map›Paper›PMID 31417681›Full record

Trial reportPharmacology research & perspectives2019

Pharmacodynamics, safety, and immunogenicity of Pelmeg

Hendrik Wessels, Dirk Lehnick, Josef Höfler, Ruediger Jankowsky, Paul Chamberlain, Karsten Roth

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Pharmacology research & perspectives, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Pharmacodynamics, safety, and immunogenicity of PelmegPharmacology research & perspectives · 2019
    Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hendrik WesselsCinfa Biotech GmbH (now part of the Mundipharma network of independent associated companies) Munich Germany.
Dirk LehnickUniversity of Lucerne Lucerne Switzerland.ORCID 0000-0003-1836-2811
Josef HöflerStaburo GmbH Munich Germany.
Ruediger JankowskyCinfa Biotech GmbH (now part of the Mundipharma network of independent associated companies) Munich Germany.
Paul ChamberlainNDA Advisory Services, Ltd, Grove House Leatherhead Surrey UK.
Karsten RothCinfa Biotech GmbH (now part of the Mundipharma network of independent associated companies) Munich Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A pharmacodynamics (PD) and immunogenicity study was conducted to investigate biosimilarity of Pelmeg

Indexed as

AntibodiesArea Under CurveBiosimilar PharmaceuticalsCross-Over StudiesDouble-Blind MethodFilgrastimHealthy VolunteersHumansMaleNeutrophilsPolyethylene GlycolsTherapeutic EquivalencyAntibodiesBiosimilar PharmaceuticalsFilgrastimpegfilgrastimPolyethylene Glycolsbiosimilarsfilgrastimhighly similarmyelosuppressive chemotherapyneutropeniaoncologypegfilgrastimsupportive care

Identifiers

PMID31417681
PMCPMC6691755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.