Evidence map›Paper›PMID 31417557›Full record

Trial reportFrontiers in immunology2019

Selective Brain Network and Cellular Responses Upon Dimethyl Fumarate Immunomodulation in Multiple Sclerosis.

Dumitru Ciolac, Felix Luessi, Gabriel Gonzalez-Escamilla, Nabin Koirala, Christian Riedel, Vinzenz Fleischer, Stefan Bittner, Julia Krämer, Sven G Meuth, Muthuraman Muthuraman and 1 more

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Dumitru CiolacDepartment of Neurology, Focus Program Translational Neuroscience (FTN), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Felix LuessiDepartment of Neurology, Focus Program Translational Neuroscience (FTN), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Gabriel Gonzalez-EscamillaDepartment of Neurology, Focus Program Translational Neuroscience (FTN), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Nabin KoiralaDepartment of Neurology, Focus Program Translational Neuroscience (FTN), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Christian RiedelDepartment of Neuroradiology, University of Kiel, Kiel, Germany.
Vinzenz FleischerDepartment of Neurology, Focus Program Translational Neuroscience (FTN), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Stefan BittnerDepartment of Neurology, Focus Program Translational Neuroscience (FTN), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Julia KrämerDepartment of Neurology With Institute of Translational Neurology, University of Münster, Münster, Germany.
Sven G MeuthDepartment of Neurology With Institute of Translational Neurology, University of Münster, Münster, Germany.
Muthuraman MuthuramanDepartment of Neurology, Focus Program Translational Neuroscience (FTN), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Sergiu GroppaDepartment of Neurology, Focus Program Translational Neuroscience (FTN), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
University Medical Center of the Johannes Gutenberg University Mainz · DEJohannes Gutenberg University Mainz · DEUniversity of Münster · DEKiel University · DE

Funding

German Research Council
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CD8-Positive T-LymphocytesCerebral CortexMultiple SclerosisAdultAgedAged, 80 and overDimethyl FumarateFemaleGray MatterHumansImmunologic FactorsLongitudinal StudiesMaleMiddle AgedNerve NetWhite MatterDimethyl FumarateImmunologic Factorsgray matter networksimmunocellular responsemultiple sclerosispersonalized therapystructural integritywhite matter networks

Identifiers

PMID31417557
PMCPMC6682686
OpenAlexW2957108272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.