Evidence map›Paper›PMID 31417430›Full record

ArticleFrontiers in physiology2019

A Vaccinomics Approach for the Identification of Tick Protective Antigens for the Control of

Marinela Contreras, Margarita Villar, José de la Fuente

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Evolution of tick vaccinology.Parasitology · 2024
    Review
  2. Universal Tick Vaccines: Candidates and Remaining Challenges.Animals : an open access journal from MDPI · 2023
    Review
  3. Review
  4. Tick Vaccines and Concealed versus Exposed Antigens.Pathogens (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
  7. Fundamental Tick Vaccinomic Approach to Evade Host Autoimmune Reaction.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  8. Review
  9. Review
  10. Interactions Between Ticks and Lyme Disease Spirochetes.Current issues in molecular biology · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Marinela ContrerasSaBio, Instituto de Investigación en Recursos Cinegéticos (IREC; CSIC-UCLM-JCCM), Ciudad Real, Spain.
Margarita VillarSaBio, Instituto de Investigación en Recursos Cinegéticos (IREC; CSIC-UCLM-JCCM), Ciudad Real, Spain.
José de la FuenteSaBio, Instituto de Investigación en Recursos Cinegéticos (IREC; CSIC-UCLM-JCCM), Ciudad Real, Spain.
Instituto de Investigación en Recursos Cinegéticos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ticks and tick-borne pathogens affect health and welfare of companion animals worldwide, and some human tick-borne diseases are associated with exposure to domestic animals. Vaccines are the most environmentally friendly alternative to acaracides for the control of tick infestations, and to reduce the risk for tick-borne diseases affecting human and animal health. However, vaccines have not been developed or successfully implemented for most vector-borne diseases. The main limitation for the development of effective vaccines is the identification of protective antigens. To address this limitation, in this study we used an experimental approach combining vaccinomics based on transcriptomics and proteomics data with vaccination trials for the identification of tick protective antigens. The study was focused on

Indexed as

DermacentordogIxodesproteomicsrabbitticktranscriptomicsvaccine

Identifiers

PMID31417430
PMCPMC6681794
OpenAlexW2960542042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.