ArticleFrontiers in integrative neuroscience2019
Reproducibility of Structural and Diffusion Tensor Imaging in the TACERN Multi-Center Study.
Article in Frontiers in integrative neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Meta-analysis of the normal diffusion tensor imaging values of the peripheral nerves in the upper limb.Scientific reports · 2023Pooled it
- MRI markers of functional connectivity and tissue microstructure in stroke-related motor rehabilitation: A systematic review.NeuroImage. Clinical · 2022Pooled it
- A two-step temporal data augmentation and supervised learning framework for predicting autism diagnosis at 36 months in patients with tuberous sclerosis complex.Computers in biology and medicine · 2026Article
- Cross-vendor reliability of functional and structural brain connectivity in a travelling cohort.Scientific reports · 2026Article
- Convolutional neural networks for automatic tuber segmentation and quantification of tuber burden in tuberous sclerosis complex.Epilepsia · 2026Article
- Impact of COVID-19 School Closures on White Matter Plasticity in the Reading Network.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Harmonization of diffusion MRI on healthy subjects using NeuroCombat and LongCombat: a B-Q MINDED brain intra- and inter-scanner study.Frontiers in neuroscience · 2025Article
- Differences between Tuberous Sclerosis Complex Patients with and without Epilepsy: The Results of a Quantitative Diffusion Tensor Imaging Study.Biomedicines · 2024Article
- Advances in Imaging of Compressive Neuropathies.Hand clinics · 2024Review
- Abnormality of Early White Matter Development in Tuberous Sclerosis Complex and Autism Spectrum Disorder: Longitudinal Analysis of Diffusion Tensor Imaging Measures.Journal of child neurology · 2024Article
- Comparison of distortion correction preprocessing pipelines for DTI in the upper limb.Magnetic resonance in medicine · 2024Article
- High-frequency Quantitative Ultrasound Imaging of Human Rotator Cuff Muscles: Assessment of Repeatability and Reproducibility.Ultrasonic imaging · 2024Article
- Blood pressure-related white matter microstructural disintegrity and associated cognitive function impairment in asymptomatic adults.Stroke and vascular neurology · 2023Article
- Future Considerations in the Diagnosis and Treatment of Compressive Neuropathies of the Upper Extremity.Journal of hand surgery global online · 2023Review
- Tubers Affecting the Fusiform Face Area Are Associated with Autism Diagnosis.Annals of neurology · 2023Article
- Peak Width of Skeletonized Mean Diffusivity: A Neuroimaging Marker for White Matter Injury.Radiology · 2023Review
- versaFlow: a versatile pipeline for resolution adapted diffusion MRI processing and its application to studying the variability of the PRIME-DE database.Frontiers in neuroinformatics · 2023Article
- Validation of cross-sectional and longitudinal ComBat harmonization methods for magnetic resonance imaging data on a travelling subject cohort.Neuroimage. Reports · 2022Article
- Validation of cardiac diffusion tensor imaging sequences: A multicentre test-retest phantom study.NMR in biomedicine · 2022Article
- What's new and what's next in diffusion MRI preprocessing.NeuroImage · 2022Review
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
backgroundMulti-site MRI studies are often necessary for recruiting sufficiently sized samples when studying rare conditions. However, they require pooling data from multiple scanners into a single data set, and therefore it is critical to evaluate the variability of quantitative MRI measures within and across scanners used in multi-site studies. The aim of this study was to evaluate the reproducibility of structural and diffusion weighted (DW) MRI measurements acquired on seven scanners at five medical centers as part of the Tuberous Sclerosis Complex Autism Center of Excellence Research Network (TACERN) multisite study.
methodsThe American College of Radiology (ACR) phantom was imaged monthly to measure reproducibility of signal intensity and uniformity within and across seven 3T scanners from General Electric, Philips, and Siemens vendors. One healthy adult male volunteer was imaged repeatedly on all seven scanners under the TACERN structural and DW protocol (5 b = 0 s/mm
resultsThe American College of Radiology Phantom signal intensity and uniformity were similar across scanners and changed little over time, with a mean intra-scanner coefficient of variation of 3.6 and 1.8%, respectively. The mean inter- and intra-scanner coefficients of variation of brain structure volumes derived from T1-weighted (T1w) images of the human phantom were 3.3 and 1.1%, respectively. The mean inter- and intra-scanner coefficients of variation of FA in white matter regions were 4.5 and 2.5%, while the mean inter- and intra-scanner coefficients of variation of MD in white matter regions were 5.4 and 1.5%.
conclusionOur results suggest that volumetric and diffusion tensor imaging (DTI) measurements are highly reproducible between and within scanners and provide typical variation amplitudes that can be used as references to interpret future findings in the TACERN network.
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