ArticleScientific reports2019
An S-cone circuit for edge detection in the primate retina.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Synaptic Organization of the Primate Retina: Toward a Human Foveal Connectome.Annual review of vision science · 2026Review
- Synaptic Inputs to OFF Parasol Ganglion Cells in Macaque Retina: An Analysis Using Serial Blockface Scanning Electron Microscopy.Brain sciences · 2026Article
- An image-computable spatio-chromatic receptive field model of the midget retinal ganglion cell mosaic across the retina.Journal of computational neuroscience · 2026Article
- S-cone-specific circuitry in the outer plexiform layer of a cone-dominant mammal.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Amacrine cell inputs to OFF midget ganglion cells in macaque retina.The Journal of physiology · 2025Article
- A circuit motif for color in the human foveal retina.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Cone-Opponent Ganglion Cells in the Primate Fovea Tuned to Noncardinal Color Directions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Synaptic Origins of the Complex Receptive Field Structure in Primate Smooth Monostratified Retinal Ganglion Cells.eNeuro · 2024Article
- Enhanced S-Cone Syndrome: Elevated Cone Counts Confer Supernormal Visual Acuity in the S-Cone Pathway.Investigative ophthalmology & visual science · 2023Article
- Comparative connectomics reveals noncanonical wiring for color vision in human foveal retina.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- From cones to color vision: a neurobiological model that explains the unique hues.Journal of the Optical Society of America. A, Optics, image science, and vision · 2023Article
- Trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina.Scientific reports · 2023Article
- Synaptic inputs to displaced intrinsically-photosensitive ganglion cells in macaque retina.Scientific reports · 2022Article
- Conserved circuits for direction selectivity in the primate retina.Current biology : CB · 2022Article
- Insight fromGenes · 2022Article
- Patterning and Development of Photoreceptors in the Human Retina.Frontiers in cell and developmental biology · 2022Review
- Synaptic inputs to broad thorny ganglion cells in macaque retina.The Journal of comparative neurology · 2021Article
- Wide-field amacrine cell inputs to ON parasol ganglion cells in macaque retina.The Journal of comparative neurology · 2020Article
- A Color Vision Circuit for Non-Image-Forming Vision in the Primate Retina.Current biology : CB · 2020Article
- Reconciling Color Vision Models With Midget Ganglion Cell Receptive Fields.Frontiers in neuroscience · 2019Review
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Midget retinal ganglion cells (RGCs) are the most common RGC type in the primate retina. Their responses have been proposed to mediate both color and spatial vision, yet the specific links between midget RGC responses and visual perception are unclear. Previous research on the dual roles of midget RGCs has focused on those comparing long (L) vs. middle (M) wavelength sensitive cones. However, there is evidence for several other rare midget RGC subtypes receiving S-cone input, but their role in color and spatial vision is uncertain. Here, we confirm the existence of the single S-cone center OFF midget RGC circuit in the central retina of macaque monkey both structurally and functionally. We investigated the receptive field properties of the S-OFF midget circuit with single cell electrophysiology and 3D electron microscopy reconstructions of the upstream circuitry. Like the well-studied L vs. M midget RGCs, the S-OFF midget RGCs have a center-surround receptive field consistent with a role in spatial vision. While spectral opponency in a primate RGC is classically assumed to contribute to hue perception, a role supporting edge detection is more consistent with the S-OFF midget RGC receptive field structure and studies of hue perception.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.