ArticleScientific reports2019
Molecular profiling and antimicrobial resistance of Shiga toxin-producing Escherichia coli O26, O45, O103, O121, O145 and O157 isolates from cattle on cow-calf operations in South Africa.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 47 citations in OpenAlex.
- Risk ranking and antimicrobial resistance of Shiga toxin-producingOne health (Amsterdam, Netherlands) · 2026Article
- Whole-Genome Sequencing ofMicroorganisms · 2026Article
- Genotypic and phenotypic evidence of extended-spectrum β-lactamase and carbapenemase-producing shigatoxigenic and intimin-producing Escherichia coli in diarrheic calves in Bangladesh: A hidden zoonotic and public health risk.Veterinary research communications · 2026Article
- Virulence genes, antimicrobial resistance profiles and phylogroups of Shiga toxin-producing Escherichia coli and atypical enteropathogenic Escherichia coli isolates from dairy cattle in South Africa.World journal of microbiology & biotechnology · 2025Article
- Colistin- and cefotaxime-resistant Shiga toxin-producing Escherichia coli (STEC) in buffalo meat.Scientific reports · 2025Article
- Shiga toxin-producing Escherichia coli plasmid diversity reveals virulence potential and control opportunities in animal hosts.Scientific reports · 2025Article
- Shiga Toxin-ProducingMicroorganisms · 2025Review
- Identification, Comparison, and Profiling of Selected Diarrhoeagenic Pathogens from Diverse Water Sources and Human and Animal Faeces Using Whole-Genome Sequencing.Microorganisms · 2025Article
- Evidence for Horizontal Transmission and Recirculation of Shiga Toxin-ProducingPathogens (Basel, Switzerland) · 2024Article
- Occurrence, serotypes and virulence characteristics of Shiga toxin-producing and Enteropathogenic Escherichia coli isolates from dairy cattle in South Africa.World journal of microbiology & biotechnology · 2024Article
- How to Improve Surveillance Program for Shiga Toxin-ProducingPathogens (Basel, Switzerland) · 2024Article
- Molecular detection of Shiga toxin and extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli isolates from sheep and goats.Molecular biology reports · 2024Article
- Molecular Detection of Shiga Toxin-ProducingInternational journal of microbiology · 2024Article
- Antimicrobial growth promoters approved in food-producing animals in South Africa induce shiga toxin-converting bacteriophages from Escherichia coli O157:H7.Gut pathogens · 2023Article
- Prevalence, antibiotic resistance, and virulence gene profile ofVeterinary world · 2023Article
- Prevalence and Molecular Characterisation of Extended-Spectrum Beta-Lactamase-Producing Shiga Toxin-ProducingPathogens (Basel, Switzerland) · 2022Article
- Article
- Identification, Characterization, and Virulence Gene Expression of Marine Enterobacteria in the Upper Gulf of Thailand.Microorganisms · 2022Article
- Isolation, Identification, and Susceptibility Profile ofVeterinary medicine international · 2022Article
- Prolonged carriage of ESBL-producing enterobacterales and potential cross-transmission among residents in geriatric long-term care facilities.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
Abstract
In this study, 140 cattle STEC isolates belonging to serogroups O157, O26, O145, O121, O103 and O45 were characterized for 38 virulence-associated genes, antimicrobial resistance profiles and genotyped by PFGE. The majority of isolates carried both stx1 and stx2 concurrently, stx2c, and stx2d; plasmid-encoded genes ehxA, espP, subA and saa but lacked katP and etpD and eaeA. Possession of eaeA was significantly associated with the presence of nle genes, katP, etpD, ureC and terC. However, saa and subA, stx1c and stx1d were only detected in eaeA negative isolates. A complete OI-122 and most non-LEE effector genes were detected in only two eaeA positive serotypes, including STEC O157:H7 and O103:H2. The eaeA gene was detected in STEC serotypes that are commonly implicated in severe humans disease and outbreaks including STEC O157:H7, STEC O145:H28 and O103:H2. PFGE revealed that the isolates were highly diverse with very low rates of antimicrobial resistance. In conclusion, only a small number of cattle STEC serotypes that possessed eaeA, had the highest number of virulence-associated genes, indicative of their high virulence. Further characterization of STEC O157:H7, STEC O145:H28 and O103:H2 using whole genome sequencing will be needed to fully understand their virulence potential for humans.
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