Evidence map›Paper›PMID 31416967›Full record

ArticleGenes & development2019

Specialization of the

Emma Kneuss, Marzia Munafò, Evelyn L Eastwood, Undine-Sophie Deumer, Jonathan B Preall, Gregory J Hannon, Benjamin Czech

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. piRNA direct the chromatin reader to its genomic targets.bioRxiv : the preprint server for biology · 2026
    Article
  5. AbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Probing direct interactions between nuclear proteins in cells with nxReLo.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Emma KneussCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.
Marzia MunafòCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.
Evelyn L EastwoodCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.
Undine-Sophie DeumerCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.
Jonathan B PreallCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Gregory J HannonCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.
Benjamin CzechCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.
Cancer Research UK · GBUniversity of Cambridge · GBCold Spring Harbor Laboratory · US

Funding

Roles of small RNAs in guarding germ cell genomesR37GM062534 · NIGMS · NEW YORK GENOME CENTER · PI HANNON, GREGORY J · 2013 to 2017
$2.0M
Cancer Research UK 21143Howard Hughes Medical InstituteNIGMS NIH HHS R37 GM062534Wellcome TrustWellcome Trust 110161/Z/15/Z
6 · The paper itself

Abstract

The PIWI-interacting RNA (piRNA) pathway is a conserved small RNA-based immune system that protects animal germ cell genomes from the harmful effects of transposon mobilization. In

Indexed as

Active Transport, Cell NucleusAnimalsDNA Transposable ElementsDrosophilaDrosophila ProteinsIntracellular Signaling Peptides and ProteinsNucleocytoplasmic Transport ProteinsRNA-Binding ProteinsRNA PrecursorsRNA, Small InterferingBoot protein, DrosophilaDNA Transposable ElementsDrosophila ProteinsIntracellular Signaling Peptides and ProteinsNucleocytoplasmic Transport ProteinsNxf3 protein, DrosophilaRNA-Binding ProteinsRNA PrecursorsRNA, Small Interferingnuclear export factorpiRNA clustersPIWI proteinsRNA exporttransposon control

Identifiers

PMID31416967
PMCPMC6719614
OpenAlexW2967128888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.