Evidence map›Paper›PMID 31416917›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Short-chain diamines are the physiological substrates of PACE family efflux pumps.

Karl A Hassan, Varsha Naidu, Jacob R Edgerton, Karla A Mettrick, Qi Liu, Leila Fahmy, Liping Li, Scott M Jackson, Irshad Ahmad, David Sharples and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Efflux, Signaling and Warfare in a Polymicrobial World.Antibiotics (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Update on Multidrug Resistance Efflux Pumps in Acinetobacter spp.Antimicrobial agents and chemotherapy · 2021
    Article
  13. Article
  14. Article
  15. Review
  16. Assembly and regulation of the chlorhexidine-specific efflux pump AceI.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Karl A HassanSchool of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW 2308, Australia; karl.hassan@newcastle.edu.au P.J.F.Henderson@leeds.ac.uk ian.paulsen@mq.edu.au.ORCID 0000-0003-2031-9679
Varsha NaiduDepartment of Molecular Sciences, Macquarie University, North Ryde, NSW 2109, Australia.
Jacob R EdgertonSchool of BioMedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.
Karla A MettrickSchool of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW 2308, Australia.
Qi LiuDepartment of Molecular Sciences, Macquarie University, North Ryde, NSW 2109, Australia.
Leila FahmySchool of BioMedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.
Liping LiDepartment of Molecular Sciences, Macquarie University, North Ryde, NSW 2109, Australia.ORCID 0000-0002-2994-6583
Scott M JacksonSchool of BioMedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.
Irshad AhmadSchool of BioMedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.
David SharplesSchool of BioMedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.
Peter J F HendersonSchool of BioMedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom karl.hassan@newcastle.edu.au P.J.F.Henderson@leeds.ac.uk ian.paulsen@mq.edu.au.
Ian T PaulsenDepartment of Molecular Sciences, Macquarie University, North Ryde, NSW 2109, Australia; karl.hassan@newcastle.edu.au P.J.F.Henderson@leeds.ac.uk ian.paulsen@mq.edu.au.ORCID 0000-0001-9015-9418
University of Leeds · GBMacquarie University · AUUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsDiaminesDrug Resistance, BacterialMembrane Transport ProteinsChlorhexidineAnti-Bacterial AgentsBacterial ProteinsChlorhexidineDiaminesMembrane Transport Proteinsdrug resistanceeffluxPACE familypolyaminestransport

Identifiers

PMID31416917
PMCPMC6731653
OpenAlexW2966928240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.