Evidence map›Paper›PMID 31416431›Full record

ArticleBMC pediatrics2019

Functional constipation in infancy and early childhood: epidemiology, risk factors, and healthcare consultation.

Anne Willemijn Walter, Anne Hovenkamp, Niranga Manjuri Devanarayana, Roshani Solanga, Shaman Rajindrajith, Marc Alexander Benninga

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
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  3. Observational
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  5. Article
  6. Article
  7. Exploring Community Perspectives on Functional Paediatric Habitual Constipation.International journal of environmental research and public health · 2024
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Anne Willemijn WalterDepartment of Pediatrics, University of Amsterdam, Academic Medical Center, H7-248, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands. hannahw91@hotmail.com.ORCID 0000-0001-9106-0508
Anne HovenkampDepartment of Pediatrics, University of Amsterdam, Academic Medical Center, H7-248, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
Niranga Manjuri DevanarayanaSenior Lecturer in Physiology, Department of Physiology, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama, 11010, Sri Lanka.
Roshani SolangaMedical Officer of Health, Ragama, Sri Lanka.
Shaman RajindrajithSenior lecturer in Paediatrics, Department of Paediatrics, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama, 11010, Sri Lanka.
Marc Alexander BenningaDepartment of Paediatric Gastroenterology and Nutrition, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
Amsterdam UMC Location University of Amsterdam · NLUniversity of Kelaniya · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional constipation (FC) is a pediatric problem that is seen frequently. However, its prevalence in Asia remains undetermined. In this study we attempted to determine the prevalence, risk factors and therapeutic modalities of FC in infants and toddlers in Sri Lanka.

methodsChildren aged 6.5 months to 4 years were selected from 14 well-baby and vaccination clinics in the Gampaha District of Sri Lanka. A questionnaire with questions regarding the socio-demographic characteristics, child's bowel habits, psycho-social risk factors and treatment modalities were filled by the mothers. FC was diagnosed according to ROME III criteria.

resultsA total of 1113 children were analyzed [(female n = 560 (50.3%) with a mean age of 20.7 months, standard deviation [SD] 11.2 months. FC was found in 89 (8.0%). FC was significantly and independently associated with underweight (14.3% vs 7.2%, p = 0.008. [OR and 95% CI: 2,3 (CI; 1.3-4.2)] and residence in an urban area (9.6% vs 5.6%, p = 0.013). [OR and 95% CI: 0.592 (CI; 0.396-0.95)]. Children subjected to violence showed a significantly higher prevalence of FC (20.0 vs 7.8%, p = 0.046). Children being overweight and children living with mothers subjected to violence showed a higher, though not statistically significant, tendency to develop FC. Children with FC visited healthcare clinics more frequently when compared to controls (19.6% vs 6.0%, p < 0.0001). However, only 24% of infants and toddlers with FC were treated specifically for the condition by a doctor.

conclusionsFC occurred in 8% of this cohort of Sri Lankan infants and toddlers. It is significantly associated with underweight and living in an urban area. Only a quarter of them received medical attention for their constipation.

trial registrationSLCP/ERC/2014/12 , December 2014.

Indexed as

Child, PreschoolConstipationCross-Sectional StudiesFemaleHumansInfantMalePrevalenceReferral and ConsultationRisk FactorsSri LankaConstipationHealthcare consultationInfantsPrevalenceRisk factorsToddlers

Identifiers

PMID31416431
PMCPMC6694472
OpenAlexW2968545412

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.