Evidence map›Paper›PMID 31416396›Full record

ReviewCell cycle (Georgetown, Tex.)2019

Skin immunity and its dysregulation in psoriasis.

Caterina Lanna, Mara Mancini, Roberta Gaziano, Maria Vittoria Cannizzaro, Marco Galluzzo, Marina Talamonti, Valentina Rovella, Margherita Annicchiarico-Petruzzelli, Gerry Melino, Ying Wang and 3 more

Abstract readReview
In one paragraph

Review in Cell cycle (Georgetown, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Update on the etiopathogenesis of psoriasis (Review).Experimental and therapeutic medicine · 2022
    Review
  18. Article
  19. Experimental Pharmacological Management of Psoriasis.Journal of experimental pharmacology · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Caterina LannaUnit of Dermatology, Department of Systems Medicine, University of Rome 'Tor Vergata' , Rome , Italy.ORCID https://orcid.org/0000-0002-3485-6275
Mara ManciniBiochemistry Laboratory, Istituto Dermopatico Immacolata (IDI-IRCCS) , Rome , Italy.ORCID https://orcid.org/0000-0001-5173-4854
Roberta GazianoDepartment of Experimental Medicine, TOR, University of Rome Tor Vergata , Rome , Italy.ORCID https://orcid.org/0000-0003-1970-2670
Maria Vittoria CannizzaroUnit of Dermatology, Department of Systems Medicine, University of Rome 'Tor Vergata' , Rome , Italy.ORCID https://orcid.org/0000-0001-6805-1005
Marco GalluzzoUnit of Dermatology, Department of Systems Medicine, University of Rome 'Tor Vergata' , Rome , Italy.ORCID https://orcid.org/0000-0002-3424-5175
Marina TalamontiUnit of Dermatology, Department of Systems Medicine, University of Rome 'Tor Vergata' , Rome , Italy.ORCID https://orcid.org/0000-0002-3070-4071
Valentina RovellaBiochemistry Laboratory, Istituto Dermopatico Immacolata (IDI-IRCCS) , Rome , Italy.
Margherita Annicchiarico-PetruzzelliBiochemistry Laboratory, Istituto Dermopatico Immacolata (IDI-IRCCS) , Rome , Italy.
Gerry MelinoBiochemistry Laboratory, Istituto Dermopatico Immacolata (IDI-IRCCS) , Rome , Italy.
Ying WangCAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences/Shanghai Jiao Tong University School of Medicine, University of Chinese Academy of Sciences, Chinese Academy of Sciences , Shanghai , China.
Yufang ShiCAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences/Shanghai Jiao Tong University School of Medicine, University of Chinese Academy of Sciences, Chinese Academy of Sciences , Shanghai , China.
Elena CampioneUnit of Dermatology, Department of Systems Medicine, University of Rome 'Tor Vergata' , Rome , Italy.ORCID https://orcid.org/0000-0001-7447-6798
Luca BianchiUnit of Dermatology, Department of Systems Medicine, University of Rome 'Tor Vergata' , Rome , Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin is a peripheral lymphoid organ, being the first immunological defense against infections as the initial interface between the organism and the external background. The maintenance of the skin immune homeostasis depends on a finely equilibrium of well-regulated relations between different cells and exogenous pathogens. Inflammatory skin diseases are directly linked to the dysregulation of this equilibrium. The present review discusses the role of the immune system, of T cells, in the etiopathogenesis of psoriasis, illustrating a potential rationale for innovative therapeutic intervention.

Indexed as

Immunity, InnateAnimalsCytokinesHumansMiceMolecular Targeted TherapyPsoriasisSkinT-LymphocytesCytokinesbiologic therapiescytokinesimmunitylymphocytesPsoriasis

Identifiers

PMID31416396
PMCPMC6773242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.