Evidence map›Paper›PMID 31416296›Full record

ArticleJournal of clinical medicine2019

Patients with ANCA-Associated Glomerulonephritis and Connective Tissue Diseases: A Comparative Study from the Maine-Anjou AAV Registry.

Fanny Guibert, Anne-Sophie Garnier, Samuel Wacrenier, Giorgina Piccoli, Assia Djema, Renaud Gansey, Julien Demiselle, Benoit Brilland, Maud Cousin, Virginie Besson and 8 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Review
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Fanny GuibertCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France.
Anne-Sophie GarnierCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France.
Samuel WacrenierCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France.
Giorgina PiccoliService de Néphrologie, Centre Hospitalier du Mans, 72037 Le Mans, France.ORCID 0000-0002-2632-4009
Assia DjemaService de Néphrologie, Centre Hospitalier de Cholet, 49300 Cholet, France.
Renaud GanseyService de Néphrologie, Centre Hospitalier de Laval, 53000 Laval, France.
Julien DemiselleCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France.ORCID 0000-0002-7255-1114
Benoit BrillandCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France.ORCID 0000-0001-9622-4014
Maud CousinCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France.
Virginie BessonCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France.
Agnès DuveauCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France.
Khuzama El NasserService de Néphrologie, Centre Hospitalier de Cholet, 49300 Cholet, France.
Jean-Philippe CoindreService de Néphrologie, Centre Hospitalier du Mans, 72037 Le Mans, France.
Anne CroueCHU Angers, Département de Pathologie Cellulaire et Tissulaire, Université d'Angers, 49100 Angers, France.
Jean-Paul Saint-AndréCHU Angers, Département de Pathologie Cellulaire et Tissulaire, Université d'Angers, 49100 Angers, France.
Alain ChevaillerCRCINA, INSERM, Université de Nantes, Université d'Angers, 49100 Angers, France.
Jean-François SubraCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France.
Jean-François AugustoCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Université d'Angers, 49100 Angers, France. jfaugusto@chu-angers.fr.ORCID 0000-0003-1498-2132
Centre Hospitalier Universitaire d'Angers · FRInserm · FRCentre Hospitalier de Lens · FRCentre Hospitalier du Mans · FRLaval Mayenne Technopole · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe overlap between antineutrophil cytoplasmic antibody (ANCA) associated glomerulonephritis (ANCA-GN) and connective tissue diseases (CTD) has been reported mainly as case series in the literature. Frequency of this association, as well as presentation and outcomes are unknown. MATERIALS AND

methodsPatients from the Maine-Anjou ANCA-associated vasculitides (AAV) registry with ANCA-GN diagnosed between 01/01/2000 and 01/01/2018, ANCA positivity, and at least six months of follow-up, were included.

results106 out of 142 patients fulfilled the inclusion criteria and were analyzed. CTD was present at ANCA-GN diagnosis in 16 (15.1%) patients. The most common CTD were rheumatoid arthritis, Sjogren syndrome and systemic sclerosis. Compared to the control group, females were more represented in the CTD group (75%,

conclusionAssociation between CTD and ANCA-GN is not a rare condition and predominantly affects females. While AAV presentation is not significantly different, CTD patients experience more frequently non-renal relapse and venous thrombotic events.

Indexed as

ANCAconnective tissue diseaseglomerulonephritisvasculitis

Identifiers

PMID31416296
PMCPMC6723780
OpenAlexW2968323849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.