Evidence map›Paper›PMID 31416228›Full record

ArticleInternational journal of molecular sciences2019

Development of an Exercise Training Protocol to Investigate Arteriogenesis in a Murine Model of Peripheral Artery Disease.

Ayko Bresler, Johanna Vogel, Daniel Niederer, Daphne Gray, Thomas Schmitz-Rixen, Kerstin Troidl

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. From Increased Fluid Shear Stress to Natural Bypass Growth.International journal of molecular sciences · 2020
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ayko BreslerDepartment of Vascular and Endovascular Surgery, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
Johanna VogelDepartment of Sports Medicine, Institute of Sport Sciences, Goethe University, Ginnheimer Landstraße 39, 60487 Frankfurt, Germany.ORCID 0000-0001-7477-0970
Daniel NiedererDepartment of Sports Medicine, Institute of Sport Sciences, Goethe University, Ginnheimer Landstraße 39, 60487 Frankfurt, Germany.
Daphne GrayDepartment of Vascular and Endovascular Surgery, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
Thomas Schmitz-RixenDepartment of Vascular and Endovascular Surgery, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.ORCID 0000-0002-6082-0006
Kerstin TroidlDepartment of Vascular and Endovascular Surgery, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany. Kerstin.troidl@mpi-bn.mpg.de.ORCID 0000-0002-0883-9949
Goethe University Frankfurt · DE

Funding

Anna-Maria and Uwe-Karsten Kühl Foundation T0188/28514/2016
6 · The paper itself

Abstract

Exercise is a treatment option in peripheral artery disease (PAD) patients to improve their clinical trajectory, at least in part induced by collateral growth. The ligation of the femoral artery (FAL) in mice is an established model to induce arteriogenesis. We intended to develop an animal model to stimulate collateral growth in mice through exercise. The training intensity assessment consisted of comparing two different training regimens in C57BL/6 mice, a treadmill implementing forced exercise and a free-to-access voluntary running wheel. The mice in the latter group covered a much greater distance than the former pre- and postoperatively. C57BL/6 mice and hypercholesterolemic ApoE-deficient (ApoE

Indexed as

Disease Models, AnimalNeovascularization, PhysiologicPhysical Conditioning, AnimalAnimalsBiomarkersDiet, High-FatFemoral ArteryMacrophagesMiceMice, Inbred C57BLMice, KnockoutMuscle, SkeletalPeripheral Arterial DiseaseRegional Blood FlowBiomarkersarteriogenesisexercise trainingfemoral artery ligationmouse modelperipheral artery diseaserunning wheelvoluntary training

Identifiers

PMID31416228
PMCPMC6720754
OpenAlexW2969194415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.