Evidence map›Paper›PMID 31415609›Full record

ArticlePloS one2019

Emergency department visits and hospitalizations among hemodialysis patients by day of the week and dialysis schedule in the United States.

Sai Zhang, Hal Morgenstern, Patrick Albertus, Brahmajee K Nallamothu, Kevin He, Rajiv Saran

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Preventable Hospitalizations and Kidney Care.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Cost of the quanta SC+ hemodialysis system for self-care in the United Kingdom.Hemodialysis international. International Symposium on Home Hemodialysis · 2022
    Review
  10. Article
  11. Overuse of Health Care in the Emergency Services in Chile.International journal of environmental research and public health · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sai ZhangKidney Epidemiology and Cost Center, School of Public Health, University of Michigan, Ann Arbor, MI, United States of America.
Hal MorgensternDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, United States of America.
Patrick AlbertusKidney Epidemiology and Cost Center, School of Public Health, University of Michigan, Ann Arbor, MI, United States of America.
Brahmajee K NallamothuInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, United States of America.
Kevin HeKidney Epidemiology and Cost Center, School of Public Health, University of Michigan, Ann Arbor, MI, United States of America.
Rajiv SaranKidney Epidemiology and Cost Center, School of Public Health, University of Michigan, Ann Arbor, MI, United States of America.ORCID 0000-0001-7317-8756
University of Michigan · US

Funding

NLM NIH HHS HHSN276201400001C
6 · The paper itself

Abstract

BACKGROUND AND

objectivePrevious reports indicated that patients on thrice-weekly hemodialysis (HD) had higher mortality rates after the 3-day interdialytic interval. However, day-of-the-week patterns of emergency department (ED) visits and hospitalizations remain under-investigated.

methodsWe conducted a retrospective cohort study of HD patients on thrice-weekly dialysis, using 2013 data from the United States Renal Data System (USRDS). We estimated crude incidence rates of ED visits and hospitalizations by day of the week and dialysis schedule (Monday, Wednesday, Friday or Tuesday, Thursday, Saturday). Using Poisson regression, we estimated case-mix adjusted rate ratios of all-cause ED visits and hospitalizations, and adjusted rates of cause-specific ED visits and hospitalizations.

resultsWe identified 241,093 eligible HD patients in 2013, who had 514,773 ED visits and 301,674 hospitalizations that year. Three distinct but related patterns of outcome events were observed. Crude and adjusted incidence rates of all-cause, cardiovascular, and infection-related ED visits and hospitalizations, but not vascular-access-related events, were higher on all three HD treatment days ("dialysis-day effect"). Rates for ED visits and hospitalizations were lower on weekends than weekdays, rising appreciably from Sunday to Monday for both dialysis schedules ("post-weekend effect"); and rates were highest after the long 3-day interval between dialysis sessions for both dialysis schedules ("interdialytic-gap effect"). In contrast, rates of hospitalizations not preceded by an ED visit were nearly the same Monday through Friday and lower on weekends for both dialysis schedules.

conclusionsHigher rates of ED visits and hospitalizations on the days of HD sessions and early in the week are a public-health concern that should stimulate research to explain these patterns and reduce the excessive morbidity and associated costs among patients on thrice-weekly HD, while improving quality of care and patient experience with dialysis.

Indexed as

Emergency Service, HospitalHospitalizationRenal DialysisAgedFemaleHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID31415609
PMCPMC6695146
OpenAlexW2969182244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.