ArticlePloS one2019
MgO nanoparticles coated with polyethylene glycol as carrier for 2-Methoxyestradiol anticancer drug.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- PMMA/pPFPA membrane with low content of modified TiOScientific reports · 2026Article
- Hydrogen production from NaBH₄ hydrolysis over chemically reduced TiO₂-based Ru nanocomposites and their antimicrobial performance.Scientific reports · 2026Article
- Comparative Evaluation of Antioxidant and Antidiabetic Activities of ZrONanomaterials (Basel, Switzerland) · 2025Article
- Efficacy of cationic polymer-coated magnesium oxide nanoparticles as anti-cancer candidates.Royal Society open science · 2025Article
- Antibacterial Potential and Biocompatibility of Chitosan/Polycaprolactone Nanofibrous Membranes Incorporated with Silver Nanoparticles.Polymers · 2024Article
- Zeolite Nanoparticles Loaded with 2-Methoxystradiol as a Novel Drug Delivery System for the Prostate Cancer Therapy.International journal of molecular sciences · 2023Article
- Metal Oxides Nanoparticles: General Structural Description, Chemical, Physical, and Biological Synthesis Methods, Role in Pesticides and Heavy Metal Removal through Wastewater Treatment.Molecules (Basel, Switzerland) · 2023Review
- Drug Delivery Systems in Regenerative Medicine: An Updated Review.Pharmaceutics · 2023Review
- Metal Oxide Nanoparticles: Review of Synthesis, Characterization and Biological Effects.Journal of functional biomaterials · 2022Review
- Microenvironmental Behaviour of Nanotheranostic Systems for Controlled Oxidative Stress and Cancer Treatment.Nanomaterials (Basel, Switzerland) · 2022Review
- Injectable niclosamide nanohybrid as an anti-SARS-CoV-2 strategy.Colloids and surfaces. B, Biointerfaces · 2021Article
- Titanium industrial residues surface modification towards its reuse as antimicrobial surfaces.Environmental science and pollution research international · 2021Article
- Urinary oestrogen steroidome as an indicator of the risk of localised prostate cancer progression.British journal of cancer · 2021Article
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- Role of capping agents in the application of nanoparticles in biomedicine and environmental remediation: recent trends and future prospects.Journal of nanobiotechnology · 2020Review
- Surface-functionalised hybrid nanoparticles for targeted treatment of cancer.IET nanobiotechnology · 2020Review
- Photocatalytic activity of graphene oxide-TiORoyal Society open science · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Novel Magnesium Oxide (MgO) nanoparticles (NPs) modified with the polymer polyethylene glycol (PEG) were synthesized as carrier for the anticancer drug 2-Methoxyestradiol (2ME) to improve its clinical application. The functionalized NPs were characterized by Infrared spectroscopy with Fourier transform to elucidate the vibration modes of this conjugate, indicating the formation of the MgO-PEG-2ME nanocomposite. The studies of absorption and liberation determined that MgO-PEG-2ME NPs incorporated 98.51 % of 2ME while liberation of 2ME was constant during 7 days at pH 2, 5 and 7.35. Finally, the MgO-PEG-2ME NPs decreased the viability of the prostate cancer cell line LNCap suggesting that this nanocomposite is suitable as a drug delivery system for anticancer prostate therapy.
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