Evidence map›Paper›PMID 31414953›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019

Pharmacokinetics of

Anne V Clough, Katherine Barry, Benjamin M Rizzo, Elizabeth R Jacobs, Said H Audi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Anne V CloughDepartment of Mathematics, Statistics, and Computer Science, Marquette University, Milwaukee, Wisconsin.
Katherine BarryDepartment of Biomedical Engineering, Marquette University, Milwaukee, Wisconsin.
Benjamin M RizzoDepartment of Mathematics, Statistics, and Computer Science, Marquette University, Milwaukee, Wisconsin.
Elizabeth R JacobsMilwaukee Veterans Affairs Medical Center, Milwaukee, Wisconsin.
Said H AudiMilwaukee Veterans Affairs Medical Center, Milwaukee, Wisconsin.
Marquette University · USMedical College of Wisconsin · USMilwaukee VA Medical Center · US

Funding

LUNG METABOLISM OF VASOACTIVE HORMONESR01HL024349 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI AUDI, SAID H · 1985 to 2010
$2.1M
SPECT Imaging and Computational Modeling for Assessment of Acute Lung InjuryR15HL129209 · NHLBI · MARQUETTE UNIVERSITY · PI SAID H AUDI · 2015 to 2026
$1.8M
Novel imaging to identify lung mitochondrial injury and predict recoveryR01HL116530 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI JACOBS, ELIZABETH R · 2013 to 2016
$1.1M
Novel Diagnostics to Detect Lung InjuryI01BX001681 · VA · CLEMENT J. ZABLOCKI VA MEDICAL CENTER · PI JACOBS, ELIZABETH R · 2013 to 2016
–
BLRD VA I01 BX001681BLRD VA I01 BX003833NHLBI NIH HHS R01 HL024349NHLBI NIH HHS R01 HL116530NHLBI NIH HHS R15 HL129209
6 · The paper itself

Abstract

Lung uptake of technetium-labeled hexamethylpropyleneamine oxime (HMPAO) increases in rat models of human acute lung injury, consistent with increases in lung tissue glutathione (GSH). Since

Indexed as

AnimalsLungMaleOrgan Culture TechniquesRadiopharmaceuticalsRatsRats, Sprague-DawleyTechnetium Tc 99m ExametazimeTomography, Emission-Computed, Single-PhotonRadiopharmaceuticalsTechnetium Tc 99m Exametazimecomputational modelingglutathionemolecular imagingoxidative stress

Identifiers

PMID31414953
PMCPMC6957362
OpenAlexW2967155708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.