Evidence map›Paper›PMID 31414316›Full record

ArticleJournal of assisted reproduction and genetics2019

Hospitalization before and after delivery in fertile, subfertile, and ART-treated women.

Judy E Stern, Chia-Ling Liu, Howard Cabral, Elizabeth Harvey, Stacey A Missmer, Hafsatou Diop, Charles C Coddington

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Judy E SternDepartment of Obstetrics & Gynecology, Dartmouth-Hitchcock, One Medical Center Drive, Lebanon, NH, 03756, USA. judy.e.stern@dartmouth.edu.ORCID http://orcid.org/0000-0002-7672-3913
Chia-Ling LiuBureau of Family Health and Nutrition, Massachusetts Department of Public Health, Boston, MA, USA.
Howard CabralDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Elizabeth HarveyBureau of Family Health and Nutrition, Massachusetts Department of Public Health, Boston, MA, USA.
Stacey A MissmerDepartment of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University, Grand Rapids, MI, USA.
Hafsatou DiopBureau of Family Health and Nutrition, Massachusetts Department of Public Health, Boston, MA, USA.
Charles C CoddingtonAtrium Health, Charlotte, NC, 28204, USA.
Massachusetts Department of Public Health · USAtrium Medical Cente · USBoston University · USDartmouth–Hitchcock Medical Center · USHarvard University · US

Funding

Women's Health After Assisted Reproductive Technology: A Population-Based StudyR01HD067270 · NICHD · DARTMOUTH-HITCHCOCK CLINIC · PI DIOP, HAFSATOU, STERN, JUDY E · 2011 to 2020
$7.4M
NICHD NIH HHS R01 HD067270NIH HHS R01HD067270
6 · The paper itself

Abstract

purposePre-pregnancy and post-delivery hospitalizations were compared as markers for health among women who conceived using assisted reproductive technology (ART), non-ART medically assisted reproduction (MAR), no treatment (unassisted subfertile), and who were fertile.

methodsWe analyzed hospital discharge data linked to Massachusetts birth certificates from 2004 to 2013 within 5 years prior to pregnancy and 8-365 days post-delivery. ART deliveries were linked from a national ART database; MAR deliveries had fertility treatment but not ART; unassisted subfertile women had subfertility but no ART or MAR; and fertile women had none of these. Prevalence of diagnoses during hospitalization was quantified. Multivariable logistic regression models with fertile deliveries as reference were adjusted for maternal age, race, education, year, and plurality (post-delivery only) with results reported as adjusted odds ratios (AORs) and 95% confidence intervals (CI).

resultsOf 170,605 privately insured, primiparous deliveries, 10,458 were ART, 3005 MAR, 1365 unassisted subfertile, and 155,777 fertile. Pre-pregnancy hospitalization occurred in 6.8% and post-delivery in 2.8% of fertile women. Subfertile groups had more pre-pregnancy hospitalizations (AOR, 95% CI: 1.84, 1.72-1.96 ART; 1.41, 1.24-1.60 MAR; 3.02, 2.62-3.47 unassisted subfertile) with endometriosis, reproductive organ disease, ectopic pregnancy/miscarriage, and disorders of menstruation, ovulation, and genital tract being common. Post-delivery hospitalizations were significantly more frequent in the ART (AOR 1.19, 95% CI 1.05-1.34) and unassisted subfertile (1.59, 1.23-2.07) groups with more digestive tract disorders, thyroid problems, and other grouped chronic disease conditions.

conclusionsGreater likelihood of hospitalization in the ART, MAR, and unassisted subfertile groups is largely explained by admissions for conditions associated with subfertility.

Indexed as

Reproductive Techniques, AssistedAdultFemaleFertilityHospitalizationHumansInfant, Low Birth WeightInfant, NewbornInfertilityMaternal AgePregnancyPregnancy, MultiplePregnancy OutcomePremature BirthAssisted reproductive technologyHospitalizationIn vitro fertilizationMedically assisted reproductionSubfertilityWomen’s health

Identifiers

PMID31414316
PMCPMC6823420
OpenAlexW2968687582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.