Evidence map›Paper›PMID 31414202›Full record

ArticleInternational journal of legal medicine2020

Optimizing DNA recovery and forensic typing of degraded blood and dental remains using a specialized extraction method, comprehensive qPCR sample characterization, and massively parallel sequencing.

Patricio Carrasco, Carolina Inostroza, Meghan Didier, Marianela Godoy, Cydne L Holt, Jonathan Tabak, Andrew Loftus

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in International journal of legal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Patricio CarrascoUniversidad de los Andes, Mons. Álvaro del Portillo 12.455, Las Condes, Santiago, Chile.
Carolina InostrozaUniversidad de los Andes, Mons. Álvaro del Portillo 12.455, Las Condes, Santiago, Chile.
Meghan DidierVerogen, Inc., 11111 Flintkote Avenue, San Diego, CA, 92121, USA. mdidier@verogen.com.ORCID http://orcid.org/0000-0001-8146-9668
Marianela GodoyUniversidad de los Andes, Mons. Álvaro del Portillo 12.455, Las Condes, Santiago, Chile.
Cydne L HoltVerogen, Inc., 11111 Flintkote Avenue, San Diego, CA, 92121, USA.
Jonathan TabakVerogen, Inc., 11111 Flintkote Avenue, San Diego, CA, 92121, USA.
Andrew LoftusInnoGenomics Technologies, LLC, 1441 Canal Street, New Orleans, LA, 70112, USA.
Universidad de Los Andes, Chile · CLReprogenetics · USHistogen (United States) · USInnoGenomics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human dental remains encountered in criminal casework evidence, missing person cases, or mass disaster tragedies provide a valuable sample source for DNA typing when suitable soft tissue is unavailable. Using traditional methods, teeth samples can be challenging to process, resulting in low-quantity and/or quality nuclear DNA and insufficient profiles for comparisons. This study examines the performance of a three-part nuclear DNA analysis workflow for teeth samples based on (1) improved dental tissue recovery using the Dental Forensic Kit (DFK

Indexed as

Forensic DentistrySequence Analysis, DNAToothAdolescentAdultAllelesChildDental CementumDental PulpDNADNA FingerprintingFemaleGenetic MarkersGenotypeHigh-Throughput Nucleotide SequencingHumansDNAGenetic MarkersDegraded DNADental Forensic Kit (DFK)ForenSeqInnoQuant HYMassively Parallel Sequencing (MPS)Single-Nucleotide Polymorphism (SNP)

Identifiers

PMID31414202
PMCPMC6949324
OpenAlexW2967158060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.