ArticleBMJ paediatrics open2019
Gabapentin for the treatment of pain manifestations in children with severe neurological impairment: a single-centre retrospective review.
Article in BMJ paediatrics open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Identification of a different DNA methylation pattern for pain related genes in children with intellectual disability: a cross-sectional study.Italian journal of pediatrics · 2026Article
- Gastrointestinal Dystonia in Children and Young People with Severe Neurological Impairment & Palliative Care Needs: A Systematic Review.Children (Basel, Switzerland) · 2025Review
- Case Report: Holistic approach to management of an infant with severe osteogenesis imperfecta in the neonatal intensive care unit.Frontiers in pediatrics · 2025Article
- Research staff's experiences of how the COVID-19 pandemic impacted recruitment for a paediatric network study.International journal of qualitative studies on health and well-being · 2024Article
- Does Gabapentin Have A Role in the Improvement of Feeding Resistance in Infants?Advanced biomedical research · 2024Article
- Relevance of Potential Contributing Factors for the Development and Maintenance of Irritability of Unknown Origin in Pediatric Palliative Care.Children (Basel, Switzerland) · 2023Article
- Antiseizure Medication-Induced Alopecia: A Literature Review.Medicines (Basel, Switzerland) · 2023Review
- Clinical characteristics of children with severe neurologic impairment: A scoping review.Journal of hospital medicine · 2023Article
- Evaluation of children with severe neurological impairment admitted to hospital with pain and irritability.BMC pediatrics · 2022Article
- Multi-Organ Dysfunction in Cerebral Palsy.Frontiers in pediatrics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pain, irritability and feeding intolerance are common symptoms affecting quality of life in children with severe neurological impairment (SNI). We performed a retrospective study to explore the use of gabapentinoid medications for symptom control in children with SNI. Patients attending the palliative care or gastroenterology department being treated with gabapentin for irritability, vomiting or pain of unknown origin were included. Information was gathered retrospectively from medical documentation. Irritability was reduced in 30 of the 42 patients included. Gabapentin was discontinued in 15 children, 12 of whom then received pregabalin. Three children had a good response to pregabalin, six a minimal improvement and three no improvement. These results support the use of gabapentinoids in this patient cohort.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.