Evidence map›Paper›PMID 31414026›Full record

ReviewJournal of patient-centered research and reviews2019

Diabetic Gastroparesis: Perspectives From a Patient and Health Care Providers.

Adam D Farmer, Caroline Bruckner-Holt, Susanne Schwartz, Emma Sadler, Sri Kadirkamanthan

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of patient-centered research and reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Suffering in Silence: Is Gastroparesis Underdiagnosed?Journal of patient-centered research and reviews · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Adam D FarmerInstitute of Applied Clinical Science, University of Keele, Keele, United Kingdom.
Caroline Bruckner-HoltDepartment of Palliative Medicine, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, United Kingdom.
Susanne SchwartzGastroparesis & Intestinal Failure Trust, Stafford, United Kingdom.
Emma SadlerDepartment of Research and Development, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, United Kingdom.
Sri KadirkamanthanDepartment of Surgery, Broomfield Hospital NHS Trust, Chelmsford, United Kingdom.
University Hospitals of North Midlands NHS Trust · GBBroomfield Hospital · GBKeele University · GBNational Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastroparesis is defined as a delay in gastric emptying in the absence of mechanical obstruction in the stomach. Gastroparesis has a number of causes, including postsurgical, secondary to medications, postinfectious, idiopathic, and as a complication of diabetes mellitus, where it is underrecognized. The cardinal symptoms of diabetic gastroparesis are nausea, early satiety, bloating, and vomiting. Diabetic gastroparesis is more common in females and has a cumulative incidence of 5% in type 1 diabetes and 1% in type 2 diabetes. It is associated with a reduction in quality of life and exerts a significant burden on health care resources. The pathophysiology of this disorder is incompletely understood. Diagnosis is made based on typical symptoms associated with the demonstration of delayed gastric emptying in the absence of gastric outlet obstruction. Gastric emptying scintigraphy is the gold standard for demonstrating delayed gastric emptying, but other methods exist including breath testing and the wireless motility capsule. Diabetic gastroparesis should be managed within a specialist multidisciplinary team, and general aspects involve dietary manipulations/nutritional support, pharmacological therapy, and surgical/endoscopic interventions. Specific pharmacological therapies include prokinetics and antiemetics, with several new medications in the drug development pipeline. Surgical/endoscopic interventions include botulinum toxin injection into the pylorus, gastric peroral endoscopic myotomy and gastric electrical stimulation. This article provides a detailed review and summary of the epidemiology, pathophysiology, investigation, and management of diabetic gastroparesis, and also gives an individual patient's perspective of living with this disabling disorder.

Indexed as

diabetesdiagnosisgastrointestinal dysmotilitygastroparesispathophysiologypatient perspective

Identifiers

PMID31414026
PMCPMC6676757
OpenAlexW2943330130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.