Evidence map›Paper›PMID 31413921›Full record

ArticleOncoimmunology

Percutaneous BCG enhances innate effector antitumor cytotoxicity during treatment of bladder cancer: a translational clinical trial.

Niannian Ji, Neelam Mukherjee, Edwin E Morales, Maggie E Tomasini, Vincent Hurez, Tyler J Curiel, Getahun Abate, Dan F Hoft, Xiang-Ru Zhao, Jon Gelfond and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04806178 (Systemic Immunological Response of Bladder Cancer Patients Under Bacillus Calmette Guérin Treatment), which is not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04806178 phase3completednot on this map

Systemic Immunological Response of Bladder Cancer Patients Under Bacillus Calmette Guérin Treatment

TypeinterventionalSponsorUniversity of Campinas, BrazilRan2021 to 2024Enrolled30ConditionsBladder Cancer, Bacillus Calmette-GuerinArmsBacillus Calmette Guerin, PLACEBO
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 36 citations in OpenAlex.

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  15. Macrophages as tools and targets in cancer therapy.Nature reviews. Drug discovery · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Niannian JiDepartment of Urology, School of Medicine, the University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Neelam MukherjeeDepartment of Urology, School of Medicine, the University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Edwin E MoralesDepartment of Urology, School of Medicine, the University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Maggie E TomasiniDepartment of Urology, School of Medicine, the University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Vincent HurezDepartment of Medicine/Hematology & Medical Oncology, School of Medicine, the University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Tyler J CurielDepartment of Medicine/Hematology & Medical Oncology, School of Medicine, the University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Getahun AbateDepartment of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University Edward A. Doisy Research Center, .St. Louis, MO, USA.
Dan F HoftDepartment of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University Edward A. Doisy Research Center, .St. Louis, MO, USA.
Xiang-Ru ZhaoDepartment of Medicine/Hematology & Medical Oncology, School of Medicine, the University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Jon GelfondDepartment of Epidemiology and Biostatistics, School of Medicine, the University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Sourindra MaitiPediatrics, M.D. Anderson Cancer Center, Houston, TX, USA.
Laurence J N CooperPediatrics, M.D. Anderson Cancer Center, Houston, TX, USA.
Robert S SvatekDepartment of Urology, School of Medicine, the University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
The University of Texas Health Science Center at San Antonio · USSaint Louis University · USThe University of Texas MD Anderson Cancer Center · US

Funding

San Antonio OAIC - Research Education Component (REC)P30AG044271 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Adam Salmon · 2015 to 2026
$14.1M
Role of gammadelta T Cells in Vaccine-Induced ImmunityR01AI048391 · NIAID · SAINT LOUIS UNIVERSITY · PI HOFT, DANIEL F. · 2002 to 2019
$6.1M
Improving immunotherapy in bladder cancer by targeting immune dysfunctionK23CA178204 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SVATEK, ROBERT SCOTT · 2014 to 2017
$674k
NCI NIH HHS K23 CA178204NIAID NIH HHS R01 AI048391NIA NIH HHS P30 AG044271
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BCGbladder cancerclinical trialPrimingvaccine

Identifiers

PMID31413921
PMCPMC6682354
OpenAlexW2946793191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.