ReviewTremor and other hyperkinetic movements (New York, N.Y.)2019
Ataxic Gait in Essential Tremor: A Disease-Associated Feature?
Review in Tremor and other hyperkinetic movements (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05170022 (Clinical Profile in Patients With Essential Tremors), which is not on this map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Profile in Patients With Essential Tremors
Who cites it
26 citing papers in PubMed, 36 citations in OpenAlex.
- Viral vector-mediated SLC9A6 gene replacement reduces cerebellar motor and molecular abnormalities in the shaker rat model of Christianson syndrome.Human molecular genetics · 2026Article
- Does the Severity of Arm Tremor in Essential Tremor Correlate with Impaired Balance?Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Magnetic resonance-guided focused ultrasound thalamotomy in essential tremor subtypes: a phenotype-based insight into gait and balance.Brain communications · 2026Article
- Predictors of Mortality in a Large Cohort of Elders with Essential Tremor.Neuroepidemiology · 2026Article
- Natural disease progression vs. DBS-related worsening in essential tremor.medRxiv : the preprint server for health sciences · 2025Article
- The cerebellar involvement in essential tremor: the connecting roads.Arquivos de neuro-psiquiatria · 2025Review
- Cognitive trajectories in older adults with essential tremor.Journal of the International Neuropsychological Society : JINS · 2025Article
- Associations Between Cognitive Profiles and Balance in Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Article
- Therapeutic Potential of Agmatine in Essential Tremor Through Regulation of Lingo-1 and Inflammatory Pathways.Brain and behavior · 2025Article
- Evaluating Postural Transition Movement Performance in Individuals with Essential Tremor via the Instrumented Timed Up and Go.Sensors (Basel, Switzerland) · 2024Article
- Featuring the Features of the Featureless Tremor: A Statement about Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024Article
- The role of plasma concentrations and drug characteristics of beta-blockers in fall risk of older persons.Pharmacology research & perspectives · 2023Article
- Associations between cognitive function and a range of significant life events in an elderly essential tremor cohort study.Journal of the neurological sciences · 2023Article
- Ability of Swept-source OCT and OCT-angiography to detect neuroretinal and vasculature changes in patients with Parkinson disease and essential tremor.Eye (London, England) · 2023Article
- Ataxias: Hereditary, Acquired, and Reversible Etiologies.Seminars in neurology · 2023Article
- Displaced center of pressure on the treated side in individuals with essential tremor after radiofrequency ablation: a longitudinal case-control study.Frontiers in neurology · 2023Article
- Association between cognitive diagnosis and a range of significant life events in an elderly essential tremor cohort: a longitudinal, prospective analysis.Frontiers in neurology · 2023Article
- Motor features associated with cognition in non-demented individuals with essential tremor.Journal of the neurological sciences · 2022Article
- New horizons in late-onset essential tremor: a pre-cognitive biomarker of dementia?Age and ageing · 2022Article
- Bayesian Interpretation of Essential Tremor Plus.Journal of clinical neurology (Seoul, Korea) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Background: While accumulating evidence suggests that balance and gait impairments are commonly seen in patients with essential tremor (ET), questions remain regarding their prevalence, their relationship with normal aging, whether they are similar to the impairments seen in spinocerebellar ataxias, their functional consequences, and whether some ET patients carry greater susceptibility. Methods: We conducted a literature search (until December 2018) on this topic. Results: We identified 23 articles on gait or balance impairments in ET. The prevalence of balance impairment (missteps on tandem walk test) was seven times higher in ET patients than controls. Gait impairments in ET included reduced speed, increased asymmetry, and impaired dynamic balance. While balance and gait problems worsened with age, ET patients were more impaired than controls, independent of age. The pattern of impairments seen in ET was qualitatively similar to that seen in spinocerebellar ataxias. Balance and gait impairments resulted in greater number of near falls in ET patients. Factors associated with balance and gait impairments in ET included age, presence of tremor in midline structures, and cognitive dysfunction. Discussion: Accumulating evidence suggests that balance and gait impairments are common in ET patients and occur to a greater extent in controls. Thus, they represent a disease-associated feature. These impairments, which are qualitatively similar to those seen in spinocerebellar ataxias, are not merely subclinical but result in difficulty performing functional tasks and increase falls risk. A subset of patients is more susceptible to balance and gait impairments. The full spectrum of impairments remains to be characterized.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.