Evidence map›Paper›PMID 31413871›Full record

SynthesisRMD open2019

Current status of use of big data and artificial intelligence in RMDs: a systematic literature review informing EULAR recommendations.

Joanna Kedra, Timothy Radstake, Aridaman Pandit, Xenofon Baraliakos, Francis Berenbaum, Axel Finckh, Bruno Fautrel, Tanja A Stamm, David Gomez-Cabrero, Christian Pristipino and 5 more

Abstract readComparative StudySystematic Review
In one paragraph

Synthesis in RMD open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joanna KedraInstitut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), UMR S 1136, Sorbonne Universite, Paris, France.ORCID 0000-0003-3535-3183
Timothy RadstakeDepartment of Rheumatology, Clinical Immunology and Laboratory for Translational Immunology, University of Utrecht Faculty of Medicine, Utrecht, The Netherlands.
Aridaman PanditDepartment of Rheumatology, Clinical Immunology and Laboratory for Translational Immunology, University of Utrecht Faculty of Medicine, Utrecht, The Netherlands.ORCID 0000-0003-2057-9737
Xenofon BaraliakosHerne, Ruhr-University, Rheumazentrum Ruhrgebiet, Bochum, Germany.
Francis BerenbaumRheumatology Department, Hospital Saint-Antoine, APHP, Paris, Île-de-France, France.
Axel FinckhDivision of Rheumatology, University Hospital of Geneva, Geneva, Switzerland.
Bruno FautrelInstitut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), UMR S 1136, Sorbonne Universite, Paris, France.
Tanja A StammSection for Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-3073-7284
David Gomez-CabreroDepartamento de Salud-Universidad Pública de Navarra, Translational Bioinformatics Unit, Navarra Biomed, Pamplona, Spain.
Christian PristipinoInterventional Cardiology Department, Ospedale San Filippo Neri, Rome, Italy.
Remy ChoquetOrange e-Health, INSERM U1142, Paris, France.
Hervé Servye-Health Services, Sanoïa, Gardanne, France.
Simon StonesSchool of Healthcare, University of Leeds, Leeds, West Yorkshire, UK.
Gerd BurmesterDepartment of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany.ORCID 0000-0001-7518-1131
Laure GossecInstitut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), UMR S 1136, Sorbonne Universite, Paris, France.ORCID 0000-0002-4528-310X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the current use of big data and artificial intelligence (AI) in the field of rheumatic and musculoskeletal diseases (RMDs). Methods: A systematic literature review was performed in PubMed MEDLINE in November 2018, with key words referring to big data, AI and RMDs. All original reports published in English were analysed. A mirror literature review was also performed outside of RMDs on the same number of articles. The number of data analysed, data sources and statistical methods used (traditional statistics, AI or both) were collected. The analysis compared findings within and beyond the field of RMDs. Results: Of 567 articles relating to RMDs, 55 met the inclusion criteria and were analysed, as well as 55 articles in other medical fields. The mean number of data points was 746 million (range 2000-5 billion) in RMDs, and 9.1 billion (range 100 000-200 billion) outside of RMDs. Data sources were varied: in RMDs, 26 (47%) were clinical, 8 (15%) biological and 16 (29%) radiological. Both traditional and AI methods were used to analyse big data (respectively, 10 (18%) and 45 (82%) in RMDs and 8 (15%) and 47 (85%) out of RMDs). Machine learning represented 97% of AI methods in RMDs and among these methods, the most represented was artificial neural network (20/44 articles in RMDs). Conclusions: Big data sources and types are varied within the field of RMDs, and methods used to analyse big data were heterogeneous. These findings will inform a European League Against Rheumatism taskforce on big data in RMDs.

Indexed as

Advisory CommitteesArtificial IntelligenceBig DataEuropeHumansInformation Storage and RetrievalMachine LearningMusculoskeletal DiseasesNeural Networks, ComputerPublicationsRadiologyRheumatic DiseasesSensitivity and Specificityartificial intelligencebig databiostatisticsmachine learningrheumatology

Identifiers

PMID31413871
PMCPMC6668041

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.